Neoplastic and nonneoplastic ovarian masses: Diagnosis on cytology

<b>Objective</b> : To evaluate the role of fine needle aspiration cytology (FNAC) in the distinction between neoplastic and nonneoplastic ovarian masses. <b> Materials and Methods</b> : One hundred and twenty patients with ovarian masses were studied. After detailed history a...

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Main Authors: Khan Nazoora, Afroz Nishat, Aqil Barina, Khan Tamkin, Ahmad Ibne
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2009-01-01
Series:Journal of Cytology
Subjects:
Online Access:http://www.jcytol.org/article.asp?issn=0970-9371;year=2009;volume=26;issue=4;spage=129;epage=133;aulast=Khan
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author Khan Nazoora
Afroz Nishat
Aqil Barina
Khan Tamkin
Ahmad Ibne
author_facet Khan Nazoora
Afroz Nishat
Aqil Barina
Khan Tamkin
Ahmad Ibne
author_sort Khan Nazoora
collection DOAJ
description <b>Objective</b> : To evaluate the role of fine needle aspiration cytology (FNAC) in the distinction between neoplastic and nonneoplastic ovarian masses. <b> Materials and Methods</b> : One hundred and twenty patients with ovarian masses were studied. After detailed history and clinical examination, ultrasound (USG)-guided FNAC was performed in 92 clinical benign cases while FNAC and/or imprints of surgically resected ovarian masses was performed in 28 clinically suspected malignant cases. The smears were stained with Papanicolaou stain and histopathological sections were stained with hematoxylin and eosin stain with inclusion of special stain whenever required. Serum b-human chorionic gonadotrophin and a-fetoprotein estimations were carried out in cytologically diagnosed germ cell tumors. <b> Results</b> : The overall sensitivity, specificity and diagnostic accuracy of FNAC in diagnosing various ovarian masses were 79.2&#x0025;, 90.6&#x0025; and 89.9&#x0025;, respectively. <b>Conclusions</b> : The clinical examination, pelvic ultrasound and FNAC were complementary and none of the methods was, in itself, diagnostic. However, USG-guided FNAC was found to be a fairly specific and accurate technique and should be employed as a routine, especially in young females with clinically benign ovarian lesions. The reasons for false diagnosis and limitations of USG and FNAC have been analyzed.
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spelling doaj.art-633f037ec8c248fd9c9db6e760f893b82022-12-22T03:56:20ZengWolters Kluwer Medknow PublicationsJournal of Cytology0970-93710974-51652009-01-01264129133Neoplastic and nonneoplastic ovarian masses: Diagnosis on cytologyKhan NazooraAfroz NishatAqil BarinaKhan TamkinAhmad Ibne<b>Objective</b> : To evaluate the role of fine needle aspiration cytology (FNAC) in the distinction between neoplastic and nonneoplastic ovarian masses. <b> Materials and Methods</b> : One hundred and twenty patients with ovarian masses were studied. After detailed history and clinical examination, ultrasound (USG)-guided FNAC was performed in 92 clinical benign cases while FNAC and/or imprints of surgically resected ovarian masses was performed in 28 clinically suspected malignant cases. The smears were stained with Papanicolaou stain and histopathological sections were stained with hematoxylin and eosin stain with inclusion of special stain whenever required. Serum b-human chorionic gonadotrophin and a-fetoprotein estimations were carried out in cytologically diagnosed germ cell tumors. <b> Results</b> : The overall sensitivity, specificity and diagnostic accuracy of FNAC in diagnosing various ovarian masses were 79.2&#x0025;, 90.6&#x0025; and 89.9&#x0025;, respectively. <b>Conclusions</b> : The clinical examination, pelvic ultrasound and FNAC were complementary and none of the methods was, in itself, diagnostic. However, USG-guided FNAC was found to be a fairly specific and accurate technique and should be employed as a routine, especially in young females with clinically benign ovarian lesions. The reasons for false diagnosis and limitations of USG and FNAC have been analyzed.http://www.jcytol.org/article.asp?issn=0970-9371;year=2009;volume=26;issue=4;spage=129;epage=133;aulast=KhanFNAC; neoplastic and nonneoplastic lesions; ovarian masses
spellingShingle Khan Nazoora
Afroz Nishat
Aqil Barina
Khan Tamkin
Ahmad Ibne
Neoplastic and nonneoplastic ovarian masses: Diagnosis on cytology
Journal of Cytology
FNAC; neoplastic and nonneoplastic lesions; ovarian masses
title Neoplastic and nonneoplastic ovarian masses: Diagnosis on cytology
title_full Neoplastic and nonneoplastic ovarian masses: Diagnosis on cytology
title_fullStr Neoplastic and nonneoplastic ovarian masses: Diagnosis on cytology
title_full_unstemmed Neoplastic and nonneoplastic ovarian masses: Diagnosis on cytology
title_short Neoplastic and nonneoplastic ovarian masses: Diagnosis on cytology
title_sort neoplastic and nonneoplastic ovarian masses diagnosis on cytology
topic FNAC; neoplastic and nonneoplastic lesions; ovarian masses
url http://www.jcytol.org/article.asp?issn=0970-9371;year=2009;volume=26;issue=4;spage=129;epage=133;aulast=Khan
work_keys_str_mv AT khannazoora neoplasticandnonneoplasticovarianmassesdiagnosisoncytology
AT afroznishat neoplasticandnonneoplasticovarianmassesdiagnosisoncytology
AT aqilbarina neoplasticandnonneoplasticovarianmassesdiagnosisoncytology
AT khantamkin neoplasticandnonneoplasticovarianmassesdiagnosisoncytology
AT ahmadibne neoplasticandnonneoplasticovarianmassesdiagnosisoncytology