Chronic Stress Triggers Expression of Immediate Early Genes and Differentially Affects the Expression of AMPA and NMDA Subunits in Dorsal and Ventral Hippocampus of Rats

Chronic Stress Triggers Expression of Immediate Early Genes and Differentially Affects the Expression of AMPA and NMDA Subunits in Dorsal and Ventral Hippocampus of Rats

Previous studies in rats have demonstrated that chronic restraint stress triggers anhedonia, depressive-like behaviors, anxiety and a reduction in dendritic spine density in hippocampal neurons. In this study, we compared the effect of repeated stress on the expression of α-amino-3-hydroxy-5-methyl-...

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Bibliographic Details
Main Authors: Anibal Pacheco, Felipe I. Aguayo, Esteban Aliaga, Mauricio Muñoz, Gonzalo García-Rojo, Felipe A. Olave, Nicolas A. Parra-Fiedler, Alexandra García-Pérez, Macarena Tejos-Bravo, Paulina S. Rojas, Claudio S. Parra, Jenny L. Fiedler
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Molecular Neuroscience
Subjects:
stress
dorsal hippocampus
ventral hippocampus
NMDA receptor subunits
AMPA receptor subunits
immediately early genes
Online Access:http://journal.frontiersin.org/article/10.3389/fnmol.2017.00244/full

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