Heterochronic shift in Hox-mediated activation of sonic hedgehog leads to morphological changes during fin development.

Heterochronic shift in Hox-mediated activation of sonic hedgehog leads to morphological changes during fin development.

We explored the molecular mechanisms of morphological transformations of vertebrate paired fin/limb evolution by comparative gene expression profiling and functional analyses. In this study, we focused on the temporal differences of the onset of Sonic hedgehog (Shh) expression in paired appendages a...

Full description

Bibliographic Details
Main Authors: Koji Sakamoto, Koh Onimaru, Keijiro Munakata, Natsuno Suda, Mika Tamura, Haruki Ochi, Mikiko Tanaka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19365553/pdf/?tool=EBI

Similar Items

Similar Items