Early warning triad for pulmonary microemboli in COVID-19 pneumonia: Pulmonary artery diameter, D-dimer and NT-proBNP
In COVID-19 patients, thrombotic and fibrinolytic events due to hyperinflammation coexist. This causes enlargement of the pulmonary artery trunk, increased D-dimer and proBNP levels. We studied the correlation of PAD, D-dimer, and NT-proBNP levels. We saw that microemboli can be predicted by using t...
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| Format: | Article |
| Language: | English |
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Society of Turaz Bilim
2022-06-01
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| Series: | Medicine Science |
| Subjects: | |
| Online Access: | http://www.ejmanager.com/fulltextpdf.php?mno=22585 |
| _version_ | 1797328176947396608 |
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| author | Mustafa Timurkaan Gulsum Altuntas Mehmet Kalayci Esra Suay Timurkaan Hakan Ayyildiz |
| author_facet | Mustafa Timurkaan Gulsum Altuntas Mehmet Kalayci Esra Suay Timurkaan Hakan Ayyildiz |
| author_sort | Mustafa Timurkaan |
| collection | DOAJ |
| description | In COVID-19 patients, thrombotic and fibrinolytic events due to hyperinflammation coexist. This causes enlargement of the pulmonary artery trunk, increased D-dimer and proBNP levels. We studied the correlation of PAD, D-dimer, and NT-proBNP levels. We saw that microemboli can be predicted by using this correlation. 908 patients treated due to Covid-19 were included in the study. The patients were divided into two groups as survivors and mortal and divided into 4 groups according to lung involvement. Demographic, laboratory, and CT data were obtained from the hospital data recording system. When comparing inflammatory parameters, D-Dimer, PAD, NT-proBNP levels, we detected a significant difference between groups. There was a positive correlation between D-dimer, PAD, and NT-proBNP levels. Lung involvement more than 50% significantly increased mortality. The diagnosis of PE in patients with COVID-19 has vital importance. Rapid, reliable, non-invasive, easily accessible and low-cost tests are important in diagnosis. We predict that PAD and concurrent D-dimer with NT-proBNP elevation will enable earlier detection of pulmonary microemboli, determine mortality and prognosis, and help to regulate anticoagulation treatments earlier. [Med-Science 2022; 11(2.000): 775-9] |
| first_indexed | 2024-03-08T06:47:06Z |
| format | Article |
| id | doaj.art-6350681ea8fc4e12b1a1c9ccce0ed33a |
| institution | Directory Open Access Journal |
| issn | 2147-0634 |
| language | English |
| last_indexed | 2024-03-08T06:47:06Z |
| publishDate | 2022-06-01 |
| publisher | Society of Turaz Bilim |
| record_format | Article |
| series | Medicine Science |
| spelling | doaj.art-6350681ea8fc4e12b1a1c9ccce0ed33a2024-02-03T07:29:11ZengSociety of Turaz BilimMedicine Science2147-06342022-06-01112775910.5455/medscience.2022.01.02522585Early warning triad for pulmonary microemboli in COVID-19 pneumonia: Pulmonary artery diameter, D-dimer and NT-proBNPMustafa Timurkaan0Gulsum Altuntas1Mehmet Kalayci2Esra Suay Timurkaan3Hakan Ayyildiz4Department of Intensive Care Unit, Elazig Fethi Sekin City Hospital, Elazig, Turkey Department of Internal Medicine, Elazig Fethi Sekin City Hospital, Elazig, Turkey. Department of Biochemistry Department, Akcakoca State Hospital, Duzce, Turkey Department of Intensive Care Unit, Elazig Fethi Sekin City Hospital, Elazig, Turkey Department of Biochemistry Department, Elazig Fethi Sekin City Hospital, Elazig, TurkeyIn COVID-19 patients, thrombotic and fibrinolytic events due to hyperinflammation coexist. This causes enlargement of the pulmonary artery trunk, increased D-dimer and proBNP levels. We studied the correlation of PAD, D-dimer, and NT-proBNP levels. We saw that microemboli can be predicted by using this correlation. 908 patients treated due to Covid-19 were included in the study. The patients were divided into two groups as survivors and mortal and divided into 4 groups according to lung involvement. Demographic, laboratory, and CT data were obtained from the hospital data recording system. When comparing inflammatory parameters, D-Dimer, PAD, NT-proBNP levels, we detected a significant difference between groups. There was a positive correlation between D-dimer, PAD, and NT-proBNP levels. Lung involvement more than 50% significantly increased mortality. The diagnosis of PE in patients with COVID-19 has vital importance. Rapid, reliable, non-invasive, easily accessible and low-cost tests are important in diagnosis. We predict that PAD and concurrent D-dimer with NT-proBNP elevation will enable earlier detection of pulmonary microemboli, determine mortality and prognosis, and help to regulate anticoagulation treatments earlier. [Med-Science 2022; 11(2.000): 775-9]http://www.ejmanager.com/fulltextpdf.php?mno=22585covid-19pulmonary embolismpulmonary artery diameterd-dimerprobnp |
| spellingShingle | Mustafa Timurkaan Gulsum Altuntas Mehmet Kalayci Esra Suay Timurkaan Hakan Ayyildiz Early warning triad for pulmonary microemboli in COVID-19 pneumonia: Pulmonary artery diameter, D-dimer and NT-proBNP Medicine Science covid-19 pulmonary embolism pulmonary artery diameter d-dimer probnp |
| title | Early warning triad for pulmonary microemboli in COVID-19 pneumonia: Pulmonary artery diameter, D-dimer and NT-proBNP |
| title_full | Early warning triad for pulmonary microemboli in COVID-19 pneumonia: Pulmonary artery diameter, D-dimer and NT-proBNP |
| title_fullStr | Early warning triad for pulmonary microemboli in COVID-19 pneumonia: Pulmonary artery diameter, D-dimer and NT-proBNP |
| title_full_unstemmed | Early warning triad for pulmonary microemboli in COVID-19 pneumonia: Pulmonary artery diameter, D-dimer and NT-proBNP |
| title_short | Early warning triad for pulmonary microemboli in COVID-19 pneumonia: Pulmonary artery diameter, D-dimer and NT-proBNP |
| title_sort | early warning triad for pulmonary microemboli in covid 19 pneumonia pulmonary artery diameter d dimer and nt probnp |
| topic | covid-19 pulmonary embolism pulmonary artery diameter d-dimer probnp |
| url | http://www.ejmanager.com/fulltextpdf.php?mno=22585 |
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