Case report: Apatinib combined with neoadjuvant therapy for primary squamous cell carcinoma of the breast: a case report
Primary squamous cell carcinoma of the breast is a rare subtype of carcinoma of chemosis for which there is no effective chemotherapy regimen. Breast squamous cell carcinoma is usually “triple negative”, with poor chemotherapy effects and poor prognosis. Here, we report a successful case of primary...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-05-01
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| Series: | Frontiers in Pharmacology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2023.1115422/full |
| _version_ | 1797828863258001408 |
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| author | Fangfang Gao Jingtai Li Haoran Liao Pingming Fan Pingming Fan Minjian Wang Yu Liu Linwei Ding Guankui Du Guankui Du Guankui Du Guankui Du |
| author_facet | Fangfang Gao Jingtai Li Haoran Liao Pingming Fan Pingming Fan Minjian Wang Yu Liu Linwei Ding Guankui Du Guankui Du Guankui Du Guankui Du |
| author_sort | Fangfang Gao |
| collection | DOAJ |
| description | Primary squamous cell carcinoma of the breast is a rare subtype of carcinoma of chemosis for which there is no effective chemotherapy regimen. Breast squamous cell carcinoma is usually “triple negative”, with poor chemotherapy effects and poor prognosis. Here, we report a successful case of primary breast squamous cell carcinoma treated with apatinib. The patient was treated with 2 cycles of apatinib. The efficacy was evaluated as partial remission, and a sublesion of approximately 4 cm fell off. |
| first_indexed | 2024-04-09T13:11:12Z |
| format | Article |
| id | doaj.art-635388a3746c408798a9be39aa077f93 |
| institution | Directory Open Access Journal |
| issn | 1663-9812 |
| language | English |
| last_indexed | 2024-04-09T13:11:12Z |
| publishDate | 2023-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pharmacology |
| spelling | doaj.art-635388a3746c408798a9be39aa077f932023-05-12T07:05:11ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122023-05-011410.3389/fphar.2023.11154221115422Case report: Apatinib combined with neoadjuvant therapy for primary squamous cell carcinoma of the breast: a case reportFangfang Gao0Jingtai Li1Haoran Liao2Pingming Fan3Pingming Fan4Minjian Wang5Yu Liu6Linwei Ding7Guankui Du8Guankui Du9Guankui Du10Guankui Du11Department of Breast Surgery, The First Affiliated Hospital of Hainan Medical University, Haikou, ChinaDepartment of Breast Surgery, The First Affiliated Hospital of Hainan Medical University, Haikou, ChinaDepartment of Breast Surgery, The First Affiliated Hospital of Hainan Medical University, Haikou, ChinaDepartment of Breast Surgery, The First Affiliated Hospital of Hainan Medical University, Haikou, ChinaGuangxi Medical University Cancer Hospital, Nanning, ChinaDepartment of Pathology, The First Affiliated Hospital of Hainan Medical University, Haikou, ChinaDepartment of Breast Surgery, The First Affiliated Hospital of Hainan Medical University, Haikou, ChinaKey Laboratory of Molecular Biology, Hainan Medical University, Haikou, ChinaDepartment of Breast Surgery, The First Affiliated Hospital of Hainan Medical University, Haikou, ChinaKey Laboratory of Molecular Biology, Hainan Medical University, Haikou, ChinaDepartment of Biochemistry and Molecular Biology, Hainan Medical University, Haikou, ChinaBiotechnology and Biochemistry Laboratory, Hainan Medical University, Haikou, ChinaPrimary squamous cell carcinoma of the breast is a rare subtype of carcinoma of chemosis for which there is no effective chemotherapy regimen. Breast squamous cell carcinoma is usually “triple negative”, with poor chemotherapy effects and poor prognosis. Here, we report a successful case of primary breast squamous cell carcinoma treated with apatinib. The patient was treated with 2 cycles of apatinib. The efficacy was evaluated as partial remission, and a sublesion of approximately 4 cm fell off.https://www.frontiersin.org/articles/10.3389/fphar.2023.1115422/fullprimary squamous cell carcinoma of the breastapatinibVEGFRtargeted therapyneoadjuvant |
| spellingShingle | Fangfang Gao Jingtai Li Haoran Liao Pingming Fan Pingming Fan Minjian Wang Yu Liu Linwei Ding Guankui Du Guankui Du Guankui Du Guankui Du Case report: Apatinib combined with neoadjuvant therapy for primary squamous cell carcinoma of the breast: a case report Frontiers in Pharmacology primary squamous cell carcinoma of the breast apatinib VEGFR targeted therapy neoadjuvant |
| title | Case report: Apatinib combined with neoadjuvant therapy for primary squamous cell carcinoma of the breast: a case report |
| title_full | Case report: Apatinib combined with neoadjuvant therapy for primary squamous cell carcinoma of the breast: a case report |
| title_fullStr | Case report: Apatinib combined with neoadjuvant therapy for primary squamous cell carcinoma of the breast: a case report |
| title_full_unstemmed | Case report: Apatinib combined with neoadjuvant therapy for primary squamous cell carcinoma of the breast: a case report |
| title_short | Case report: Apatinib combined with neoadjuvant therapy for primary squamous cell carcinoma of the breast: a case report |
| title_sort | case report apatinib combined with neoadjuvant therapy for primary squamous cell carcinoma of the breast a case report |
| topic | primary squamous cell carcinoma of the breast apatinib VEGFR targeted therapy neoadjuvant |
| url | https://www.frontiersin.org/articles/10.3389/fphar.2023.1115422/full |
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