Subdued, a TMEM16 family Ca2+-activated Cl− channel in Drosophila melanogaster with an unexpected role in host defense
TMEM16A and TMEM16B are calcium-activated chloride channels (CaCCs) with important functions in mammalian physiology. Whether distant relatives of the vertebrate TMEM16 families also form CaCCs is an intriguing open question. Here we report that a TMEM16 family member from Drosophila melanogaster, S...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2013-11-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/00862 |