Prevalence of sickle cell trait in blood donors in the Midwest region of the State of Minas Gerais
Introduction: Although sickle cell trait is considered a benign condition, there are studies showing that it presents relevant clinical manifestations, which makes it important to carry out studies to know its prevalence. Objective: To estimate the prevalence of sickle cell trait in blood donors...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Associação Médica de Minas Gerais
2022-03-01
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| Series: | Revista Médica de Minas Gerais |
| Subjects: | |
| Online Access: | http://www.rmmg.org/artigo/detalhes/3875 |
| Summary: | Introduction: Although sickle cell trait is considered a benign condition,
there are studies showing that it presents relevant clinical manifestations,
which makes it important to carry out studies to know its prevalence.
Objective: To estimate the prevalence of sickle cell trait in blood donors
in the Midwest region of the state of Minas Gerais (MG). Methods:
Information on the presence of HbS in the blood, ethnicity, gender,
education, age, hemoglobin levels and origin of blood donors were
consulted in the Hemote Plus system of the Hemominas Foundation
(FH). Results: The mean age of blood donors in the Midwest region
of MG was 34.4±11.3 years, 51.4% were male, 52.8% self-declared
white, 53.3% had up to high school and the mean hemoglobin levels
were 15.1±1.3g/dL. The prevalence of sickle cell trait was 2.2% in
this population. Among the donors with sickle cell trait, there was a
higher frequency of self-declared brown, followed by self-declared white
(30.7%) and self-declared black (26.5%), aged 21 to 30 years (31.9%)
and 31 to 40 years (30.7%) and females (53.9%) were more prevalent
and the mean hemoglobin levels were 14.8±1.3 g/dL. Conclusion: The
prevalence of sickle cell trait found in our study was 2.2%, which is
similar to that found in the Brazilian population and is slightly lower
than in the state of MG. These findings contribute to other prevalence
studies in Brazil. |
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| ISSN: | 0103-880X 2238-3182 |