Prevalence of sickle cell trait in blood donors in the Midwest region of the State of Minas Gerais
Introduction: Although sickle cell trait is considered a benign condition, there are studies showing that it presents relevant clinical manifestations, which makes it important to carry out studies to know its prevalence. Objective: To estimate the prevalence of sickle cell trait in blood donors...
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| Format: | Article |
| Language: | English |
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Associação Médica de Minas Gerais
2022-03-01
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| Series: | Revista Médica de Minas Gerais |
| Subjects: | |
| Online Access: | http://www.rmmg.org/artigo/detalhes/3875 |
| _version_ | 1817991342941274112 |
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| author | Ladeira, Valéria Sutana Oliveira, Marina Mendes Rios, Danyelle Romana Alves |
| author_facet | Ladeira, Valéria Sutana Oliveira, Marina Mendes Rios, Danyelle Romana Alves |
| author_sort | Ladeira, Valéria Sutana |
| collection | DOAJ |
| description | Introduction: Although sickle cell trait is considered a benign condition,
there are studies showing that it presents relevant clinical manifestations,
which makes it important to carry out studies to know its prevalence.
Objective: To estimate the prevalence of sickle cell trait in blood donors
in the Midwest region of the state of Minas Gerais (MG). Methods:
Information on the presence of HbS in the blood, ethnicity, gender,
education, age, hemoglobin levels and origin of blood donors were
consulted in the Hemote Plus system of the Hemominas Foundation
(FH). Results: The mean age of blood donors in the Midwest region
of MG was 34.4±11.3 years, 51.4% were male, 52.8% self-declared
white, 53.3% had up to high school and the mean hemoglobin levels
were 15.1±1.3g/dL. The prevalence of sickle cell trait was 2.2% in
this population. Among the donors with sickle cell trait, there was a
higher frequency of self-declared brown, followed by self-declared white
(30.7%) and self-declared black (26.5%), aged 21 to 30 years (31.9%)
and 31 to 40 years (30.7%) and females (53.9%) were more prevalent
and the mean hemoglobin levels were 14.8±1.3 g/dL. Conclusion: The
prevalence of sickle cell trait found in our study was 2.2%, which is
similar to that found in the Brazilian population and is slightly lower
than in the state of MG. These findings contribute to other prevalence
studies in Brazil. |
| first_indexed | 2024-04-14T01:11:09Z |
| format | Article |
| id | doaj.art-63583e9546a64e42b0e603d055bf106d |
| institution | Directory Open Access Journal |
| issn | 0103-880X 2238-3182 |
| language | English |
| last_indexed | 2024-04-14T01:11:09Z |
| publishDate | 2022-03-01 |
| publisher | Associação Médica de Minas Gerais |
| record_format | Article |
| series | Revista Médica de Minas Gerais |
| spelling | doaj.art-63583e9546a64e42b0e603d055bf106d2022-12-22T02:21:02ZengAssociação Médica de Minas GeraisRevista Médica de Minas Gerais0103-880X2238-31822022-03-0132e-3210210.5935/2238-3182.2022e32102Prevalence of sickle cell trait in blood donors in the Midwest region of the State of Minas GeraisLadeira, Valéria Sutana0https://orcid.org/0000-0002-3837-2964Oliveira, Marina Mendes 1https://orcid.org/0000-0002-6182-3372Rios, Danyelle Romana Alves2https://orcid.org/0000-0001-6377-241XUniversidade Federal de São João del-Rei - UFSJ, Campus Centro Oeste Dona Lindu Divinópolis, MG-Brasil. / Fundação Hemominas, Hemonúcleo de Divinópolis. Divinópolis, MG, Brasil.Universidade Federal de São João del-Rei - UFSJ, Campus Centro Oeste Dona Lindu Divinópolis, MG-Brasil. / Fundação Hemominas, Hemonúcleo de Divinópolis. Divinópolis, MG, Brasil.Universidade Federal de São João del-Rei - UFSJ, Campus Centro Oeste Dona Lindu Divinópolis, MG-Brasil.Introduction: Although sickle cell trait is considered a benign condition, there are studies showing that it presents relevant clinical manifestations, which makes it important to carry out studies to know its prevalence. Objective: To estimate the prevalence of sickle cell trait in blood donors in the Midwest region of the state of Minas Gerais (MG). Methods: Information on the presence of HbS in the blood, ethnicity, gender, education, age, hemoglobin levels and origin of blood donors were consulted in the Hemote Plus system of the Hemominas Foundation (FH). Results: The mean age of blood donors in the Midwest region of MG was 34.4±11.3 years, 51.4% were male, 52.8% self-declared white, 53.3% had up to high school and the mean hemoglobin levels were 15.1±1.3g/dL. The prevalence of sickle cell trait was 2.2% in this population. Among the donors with sickle cell trait, there was a higher frequency of self-declared brown, followed by self-declared white (30.7%) and self-declared black (26.5%), aged 21 to 30 years (31.9%) and 31 to 40 years (30.7%) and females (53.9%) were more prevalent and the mean hemoglobin levels were 14.8±1.3 g/dL. Conclusion: The prevalence of sickle cell trait found in our study was 2.2%, which is similar to that found in the Brazilian population and is slightly lower than in the state of MG. These findings contribute to other prevalence studies in Brazil.http://www.rmmg.org/artigo/detalhes/3875sickle cell traitblood donorsprevalence |
| spellingShingle | Ladeira, Valéria Sutana Oliveira, Marina Mendes Rios, Danyelle Romana Alves Prevalence of sickle cell trait in blood donors in the Midwest region of the State of Minas Gerais Revista Médica de Minas Gerais sickle cell trait blood donors prevalence |
| title | Prevalence of sickle cell trait in blood donors in the Midwest region of the State of Minas Gerais |
| title_full | Prevalence of sickle cell trait in blood donors in the Midwest region of the State of Minas Gerais |
| title_fullStr | Prevalence of sickle cell trait in blood donors in the Midwest region of the State of Minas Gerais |
| title_full_unstemmed | Prevalence of sickle cell trait in blood donors in the Midwest region of the State of Minas Gerais |
| title_short | Prevalence of sickle cell trait in blood donors in the Midwest region of the State of Minas Gerais |
| title_sort | prevalence of sickle cell trait in blood donors in the midwest region of the state of minas gerais |
| topic | sickle cell trait blood donors prevalence |
| url | http://www.rmmg.org/artigo/detalhes/3875 |
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