Lamotrigine Effects on Breastfed Infants
Lamotrigine is a safe anti-epileptic drug among pregnant and lactating women. Some concerns exist regarding the safety of lamotrigine during breastfeeding and related neonatal complications. In this brief review, this matter was evaluated and discussed. In this review study, the medical literature a...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2015-10-01
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| Series: | Acta Medica Iranica |
| Subjects: | |
| Online Access: | https://acta.tums.ac.ir/index.php/acta/article/view/4264 |
| _version_ | 1818827134642159616 |
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| author | Hosein Dalili Fatemeh Nayeri Mamak Shariat Leila Asgarzadeh |
| author_facet | Hosein Dalili Fatemeh Nayeri Mamak Shariat Leila Asgarzadeh |
| author_sort | Hosein Dalili |
| collection | DOAJ |
| description | Lamotrigine is a safe anti-epileptic drug among pregnant and lactating women. Some concerns exist regarding the safety of lamotrigine during breastfeeding and related neonatal complications. In this brief review, this matter was evaluated and discussed. In this review study, the medical literature available in search databases such as Embase, Scopus, PubMed, and Medline and even also local medical search engines were evaluated. The results indicated that lamotrigine is a safe anti-epileptic drug for breastfeeding women with rare and usually mild adverse effects among neonates exposed to high milk concentration of this drug and its metabolites. However, close periodical monitoring for infants whose mothers are utilizing lamotrigine is recommended to decrease the probability of severe side effects among them. |
| first_indexed | 2024-12-19T00:38:44Z |
| format | Article |
| id | doaj.art-63593e92732d419ea44334e2137d3bc3 |
| institution | Directory Open Access Journal |
| issn | 0044-6025 1735-9694 |
| language | English |
| last_indexed | 2024-12-19T00:38:44Z |
| publishDate | 2015-10-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Acta Medica Iranica |
| spelling | doaj.art-63593e92732d419ea44334e2137d3bc32022-12-21T20:44:40ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942015-10-015374240Lamotrigine Effects on Breastfed InfantsHosein Dalili0Fatemeh Nayeri1Mamak Shariat2Leila Asgarzadeh3Department of Neonatology, Breast Feeding Research Center, Tehran University of Medical Sciences, Tehran, IranDepartment of Neonatology, Breast Feeding Research Center, Tehran University of Medical Sciences, Tehran, IranDepartment of Maternal and Child Health, Maternal-Fetal-Neonatal Research Center, Tehran University of Medical Sciences, Tehran, IranDepartment of Medicine, Breast Feeding Research Center, Tehran University of Medical Sciences, Tehran, IranLamotrigine is a safe anti-epileptic drug among pregnant and lactating women. Some concerns exist regarding the safety of lamotrigine during breastfeeding and related neonatal complications. In this brief review, this matter was evaluated and discussed. In this review study, the medical literature available in search databases such as Embase, Scopus, PubMed, and Medline and even also local medical search engines were evaluated. The results indicated that lamotrigine is a safe anti-epileptic drug for breastfeeding women with rare and usually mild adverse effects among neonates exposed to high milk concentration of this drug and its metabolites. However, close periodical monitoring for infants whose mothers are utilizing lamotrigine is recommended to decrease the probability of severe side effects among them.https://acta.tums.ac.ir/index.php/acta/article/view/4264LamotrigineEffectBreastfed Infants |
| spellingShingle | Hosein Dalili Fatemeh Nayeri Mamak Shariat Leila Asgarzadeh Lamotrigine Effects on Breastfed Infants Acta Medica Iranica Lamotrigine Effect Breastfed Infants |
| title | Lamotrigine Effects on Breastfed Infants |
| title_full | Lamotrigine Effects on Breastfed Infants |
| title_fullStr | Lamotrigine Effects on Breastfed Infants |
| title_full_unstemmed | Lamotrigine Effects on Breastfed Infants |
| title_short | Lamotrigine Effects on Breastfed Infants |
| title_sort | lamotrigine effects on breastfed infants |
| topic | Lamotrigine Effect Breastfed Infants |
| url | https://acta.tums.ac.ir/index.php/acta/article/view/4264 |
| work_keys_str_mv | AT hoseindalili lamotrigineeffectsonbreastfedinfants AT fatemehnayeri lamotrigineeffectsonbreastfedinfants AT mamakshariat lamotrigineeffectsonbreastfedinfants AT leilaasgarzadeh lamotrigineeffectsonbreastfedinfants |