Epidemiology of Inflammatory Bowel Diseases (IBD) in Iran: A Review of 740 Patients in Fars Province, Southern Iran
Background Although the prevalence and incidence of Inflammatory Bowel Disease (IBD) are reaching a stable status in most of the industrialized countries, Asian countries have faced with an increasing number of IBD patients in the last two decades. However, due to the lack of national registry syst...
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| Format: | Article |
| Language: | English |
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Shiraz University of Medical Sciences
2013-06-01
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| Series: | Iranian Journal of Colorectal Research |
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| Online Access: | https://colorectalresearch.sums.ac.ir/article_45441_b0ad3cfc6ac22a73cda13ffd968c9815.pdf |
| _version_ | 1818989017199280128 |
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| author | Seyed Alireza Taghavi Ali Reza Safarpour Seyed Vahid Hosseini Hesameddin Noroozi Maral Safarpour Sala Rahimikazerooni |
| author_facet | Seyed Alireza Taghavi Ali Reza Safarpour Seyed Vahid Hosseini Hesameddin Noroozi Maral Safarpour Sala Rahimikazerooni |
| author_sort | Seyed Alireza Taghavi |
| collection | DOAJ |
| description | Background Although the prevalence and incidence of Inflammatory Bowel Disease (IBD) are reaching a stable status in most of the industrialized countries, Asian countries have faced with an increasing number of IBD patients in the last two decades. However, due to the lack of national registry system, a limited amount of data is available on the epidemiology of IBD in Iran, particularly the southern parts of the country. Objectives The aim of this retrospective analytic study is clarification of multiple aspects of epidemiological factors of IBD patients in area of southern Iran. Patients and Methods Between 1989 and 2010, 740 patients with IBD, 620 ones with ulcerative colitis (UC) and 120 ones with crohn’s diseases (CD) were diagnosed as IBD cases and referred to our center. Then, their demographic characteristics, disease-related manifestations, complications, and their chief complaints were analyzed, retrospectively. Results The mean age at diagnosis was 34.68 ± 1.44 (range: 8 – 79 years) for UC patients and 32.97 ± 1.34 (range: 9 – 80 years) for CD ones. The male/female ratio was 0.9/1 and 0.98/1 for UC and CD patients, respectively. In comparison to rural patients, more urban ones with both UC and CD were registered (86.4 % with UC and 91.74% with CD). No significant change was detected in onset-diagnosis lag time in IBD patients during the study. In this study, a significant positive relationship was found between the type of the disease and positive family history, CD > UC, (χ2(6df) = 14.56, P = 0.024). Furthermore, bloody diarrhea (69.4%) and abdominal pain (54.3%) were the most prevalent presentations in UC and CD patients, respectively. Besides, massive bleeding was the most prevalent complication for both UC and CD patients (32.9% and 19.8% respectively). In addition, 289 UC (46.6%) and 39 CD (33.7%) patients had experience at least one relapse during their course of disease. Nevertheless, no significant correlation was observed between the season of the onset and the type of the disease in UC and CD patients (χ2(6df) = 6.09, P = 0.41). Also, no significant relationship was detected between smoking and the type of disease (χ2(2df) = 3.79, P = 0.13). Conclusions An obvious increase in the number of IBD patients has been detected in our population during the past decades. This can be attributed to either improvement in the patients’ and the physicians’ knowledge and availability of diagnostic tools or a real increase in the incidence rate of the disease. In either case, this alarming increase should be taken into consideration by both the health authorities (regarding the significant burden) and the researchers of the field in our society. |
| first_indexed | 2024-12-20T19:31:47Z |
| format | Article |
| id | doaj.art-63599345dec74559b3edad73a3414ad8 |
| institution | Directory Open Access Journal |
| issn | 2783-2430 |
| language | English |
| last_indexed | 2024-12-20T19:31:47Z |
| publishDate | 2013-06-01 |
| publisher | Shiraz University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Colorectal Research |
| spelling | doaj.art-63599345dec74559b3edad73a3414ad82022-12-21T19:28:45ZengShiraz University of Medical SciencesIranian Journal of Colorectal Research2783-24302013-06-01111210.17795/acr-1147745441Epidemiology of Inflammatory Bowel Diseases (IBD) in Iran: A Review of 740 Patients in Fars Province, Southern IranSeyed Alireza Taghavi0Ali Reza SafarpourSeyed Vahid HosseiniHesameddin Noroozi1Maral Safarpour2Sala Rahimikazerooni3Gastroenterohepatology Research Center, Nemazi hospital, Shiraz University of Medical Sciences, Shiraz, IR IranNutrition and Health school, Shiraz University of Medical Sciences, Shiraz, IR IranPharmacy school, International brunch of Shiraz University of Medical Sciences, Shiraz, IR IranColorectal Research Center, Faghihi hospital, Shiraz University of Medical Sciences, Shiraz, IR IranBackground Although the prevalence and incidence of Inflammatory Bowel Disease (IBD) are reaching a stable status in most of the industrialized countries, Asian countries have faced with an increasing number of IBD patients in the last two decades. However, due to the lack of national registry system, a limited amount of data is available on the epidemiology of IBD in Iran, particularly the southern parts of the country. Objectives The aim of this retrospective analytic study is clarification of multiple aspects of epidemiological factors of IBD patients in area of southern Iran. Patients and Methods Between 1989 and 2010, 740 patients with IBD, 620 ones with ulcerative colitis (UC) and 120 ones with crohn’s diseases (CD) were diagnosed as IBD cases and referred to our center. Then, their demographic characteristics, disease-related manifestations, complications, and their chief complaints were analyzed, retrospectively. Results The mean age at diagnosis was 34.68 ± 1.44 (range: 8 – 79 years) for UC patients and 32.97 ± 1.34 (range: 9 – 80 years) for CD ones. The male/female ratio was 0.9/1 and 0.98/1 for UC and CD patients, respectively. In comparison to rural patients, more urban ones with both UC and CD were registered (86.4 % with UC and 91.74% with CD). No significant change was detected in onset-diagnosis lag time in IBD patients during the study. In this study, a significant positive relationship was found between the type of the disease and positive family history, CD > UC, (χ2(6df) = 14.56, P = 0.024). Furthermore, bloody diarrhea (69.4%) and abdominal pain (54.3%) were the most prevalent presentations in UC and CD patients, respectively. Besides, massive bleeding was the most prevalent complication for both UC and CD patients (32.9% and 19.8% respectively). In addition, 289 UC (46.6%) and 39 CD (33.7%) patients had experience at least one relapse during their course of disease. Nevertheless, no significant correlation was observed between the season of the onset and the type of the disease in UC and CD patients (χ2(6df) = 6.09, P = 0.41). Also, no significant relationship was detected between smoking and the type of disease (χ2(2df) = 3.79, P = 0.13). Conclusions An obvious increase in the number of IBD patients has been detected in our population during the past decades. This can be attributed to either improvement in the patients’ and the physicians’ knowledge and availability of diagnostic tools or a real increase in the incidence rate of the disease. In either case, this alarming increase should be taken into consideration by both the health authorities (regarding the significant burden) and the researchers of the field in our society.https://colorectalresearch.sums.ac.ir/article_45441_b0ad3cfc6ac22a73cda13ffd968c9815.pdfinflammatory bowel diseases (ibd)southern iranepidemiology |
| spellingShingle | Seyed Alireza Taghavi Ali Reza Safarpour Seyed Vahid Hosseini Hesameddin Noroozi Maral Safarpour Sala Rahimikazerooni Epidemiology of Inflammatory Bowel Diseases (IBD) in Iran: A Review of 740 Patients in Fars Province, Southern Iran Iranian Journal of Colorectal Research inflammatory bowel diseases (ibd) southern iran epidemiology |
| title | Epidemiology of Inflammatory Bowel Diseases (IBD) in Iran: A Review of 740 Patients in Fars Province, Southern Iran |
| title_full | Epidemiology of Inflammatory Bowel Diseases (IBD) in Iran: A Review of 740 Patients in Fars Province, Southern Iran |
| title_fullStr | Epidemiology of Inflammatory Bowel Diseases (IBD) in Iran: A Review of 740 Patients in Fars Province, Southern Iran |
| title_full_unstemmed | Epidemiology of Inflammatory Bowel Diseases (IBD) in Iran: A Review of 740 Patients in Fars Province, Southern Iran |
| title_short | Epidemiology of Inflammatory Bowel Diseases (IBD) in Iran: A Review of 740 Patients in Fars Province, Southern Iran |
| title_sort | epidemiology of inflammatory bowel diseases ibd in iran a review of 740 patients in fars province southern iran |
| topic | inflammatory bowel diseases (ibd) southern iran epidemiology |
| url | https://colorectalresearch.sums.ac.ir/article_45441_b0ad3cfc6ac22a73cda13ffd968c9815.pdf |
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