Human mini-blood–brain barrier models for biomedical neuroscience research: a review

Human mini-blood–brain barrier models for biomedical neuroscience research: a review

Abstract The human blood–brain barrier (BBB) is a unique multicellular structure that is in critical demand for fundamental neuroscience studies and therapeutic evaluation. Despite substantial achievements in creating in vitro human BBB platforms, challenges in generating specifics of physiopatholog...

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Bibliographic Details
Main Authors: Minh Tran, Chaejeong Heo, Luke P. Lee, Hansang Cho
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2022-12-01
Series:Biomaterials Research
Subjects:
Blood–brain barrier
Human mini-brains
Neurological disorder
Personalized medicine
Online Access:https://doi.org/10.1186/s40824-022-00332-z

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