Truncated isoforms of GPSM2 containing the GoLoco motif region promote CD4+ T-cell migration in SLE

Truncated isoforms of GPSM2 containing the GoLoco motif region promote CD4+ T-cell migration in SLE

Objective SLE is an autoimmune disease with a complex pathogenesis. T-cell infiltration into organs contributes to inflammation and organ damage in SLE. Recently, G-protein signalling modulator 2 (GPSM2) has been shown to be implicated in T-cell migration.Methods We analysed the expression levels of...

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Bibliographic Details
Main Authors: Anja Meyer, Joanna Schiller, David M Kofler, Ruth L Esser, Carolin Brück, Jan Thiele, Viktoria Golumba-Nagy, Eva Steinbach-Knödgen, Shuaifeng Yan, Carola tho Pesch, David Stahl
Format: Article
Language:English
Published: BMJ Publishing Group 2022-07-01
Series:Lupus Science and Medicine
Online Access:https://lupus.bmj.com/content/9/1/e000742.full

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