Perioperative glycemic control in patients who underwent cardiac transplantation and effect on the outcome at discharge in a tertiary care centre
Objectives: To study the glycemic status and insulin requirements in patients who underwent cardiac transplantation and to compare it among patients with and without diabetes mellitus. To compare preoperative glycemic status and perioperative insulin requirements with the outcome. Methods and Materi...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2020-01-01
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| Series: | Indian Journal of Endocrinology and Metabolism |
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| Online Access: | http://www.ijem.in/article.asp?issn=2230-8210;year=2020;volume=24;issue=3;spage=270;epage=274;aulast=Kumbar |
| _version_ | 1818231081554411520 |
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| author | Lohit Kumbar Sandeep Donagaon U M Nagamalesh Ravi Shankar Shetty Pramila Kalra |
| author_facet | Lohit Kumbar Sandeep Donagaon U M Nagamalesh Ravi Shankar Shetty Pramila Kalra |
| author_sort | Lohit Kumbar |
| collection | DOAJ |
| description | Objectives: To study the glycemic status and insulin requirements in patients who underwent cardiac transplantation and to compare it among patients with and without diabetes mellitus. To compare preoperative glycemic status and perioperative insulin requirements with the outcome. Methods and Materials: The retrospective data of the glycemic status of patients before and after cardiac transplantation were collected and analyzed. Different variables like HbA1c, creatinine, age, BMI, and glycemic status were compared with the outcome. Results: A total of 18 patients with a mean age of 46.72 ± 16.94 years (mean ± SD) and a median age of 48.5 years underwent cardiac transplantation. The mean preoperative glycosylated hemoglobin (HbA1c) was 8.75 ± 2.15% (72 ± 2.36 mmol/mol) and 5.82 ± 0.45% (40 ± 4.89 mmol/mol) in patients with and without diabetes mellitus, respectively. The mean insulin requirement of insulin on postoperative days 0, 1, 2, and 3 was 1.396, 0.503, 0.490, and 0.537 (IU/kg/day) in patients with diabetes, whereas in patients without diabetes mellitus it was 1.955, 0.561, 1.19, and 0.61 (IU/kg/day), respectively. The mean insulin requirement at the time of discharge was 0.698 ± 0.43 IU/kg/day (mean ± SD) and 1.285 ± 1 IU/kg/day (mean ± SD) (p = 0.36) in patients with and without diabetes mellitus, respectively (p = 0.53, 0.11, 0.41, and 0.32, respectively). There was no association with the outcome when analyzed with different variables like HbA1c, creatinine, BMI, age, hemoglobin, insulin requirements, and glycemic status. Conclusions: Perioperative glycemic control is crucial for successful cardiac transplantation irrespective of diabetic status. |
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| format | Article |
| id | doaj.art-636896aad4f04b84b2fffddfd05a3e0b |
| institution | Directory Open Access Journal |
| issn | 2230-8210 |
| language | English |
| last_indexed | 2024-12-12T10:44:43Z |
| publishDate | 2020-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Endocrinology and Metabolism |
| spelling | doaj.art-636896aad4f04b84b2fffddfd05a3e0b2022-12-22T00:26:56ZengWolters Kluwer Medknow PublicationsIndian Journal of Endocrinology and Metabolism2230-82102020-01-0124327027410.4103/ijem.IJEM_121_20Perioperative glycemic control in patients who underwent cardiac transplantation and effect on the outcome at discharge in a tertiary care centreLohit KumbarSandeep DonagaonU M NagamaleshRavi Shankar ShettyPramila KalraObjectives: To study the glycemic status and insulin requirements in patients who underwent cardiac transplantation and to compare it among patients with and without diabetes mellitus. To compare preoperative glycemic status and perioperative insulin requirements with the outcome. Methods and Materials: The retrospective data of the glycemic status of patients before and after cardiac transplantation were collected and analyzed. Different variables like HbA1c, creatinine, age, BMI, and glycemic status were compared with the outcome. Results: A total of 18 patients with a mean age of 46.72 ± 16.94 years (mean ± SD) and a median age of 48.5 years underwent cardiac transplantation. The mean preoperative glycosylated hemoglobin (HbA1c) was 8.75 ± 2.15% (72 ± 2.36 mmol/mol) and 5.82 ± 0.45% (40 ± 4.89 mmol/mol) in patients with and without diabetes mellitus, respectively. The mean insulin requirement of insulin on postoperative days 0, 1, 2, and 3 was 1.396, 0.503, 0.490, and 0.537 (IU/kg/day) in patients with diabetes, whereas in patients without diabetes mellitus it was 1.955, 0.561, 1.19, and 0.61 (IU/kg/day), respectively. The mean insulin requirement at the time of discharge was 0.698 ± 0.43 IU/kg/day (mean ± SD) and 1.285 ± 1 IU/kg/day (mean ± SD) (p = 0.36) in patients with and without diabetes mellitus, respectively (p = 0.53, 0.11, 0.41, and 0.32, respectively). There was no association with the outcome when analyzed with different variables like HbA1c, creatinine, BMI, age, hemoglobin, insulin requirements, and glycemic status. Conclusions: Perioperative glycemic control is crucial for successful cardiac transplantation irrespective of diabetic status.http://www.ijem.in/article.asp?issn=2230-8210;year=2020;volume=24;issue=3;spage=270;epage=274;aulast=Kumbarcardiac transplantationdiabetes mellitusinsulinperioperative |
| spellingShingle | Lohit Kumbar Sandeep Donagaon U M Nagamalesh Ravi Shankar Shetty Pramila Kalra Perioperative glycemic control in patients who underwent cardiac transplantation and effect on the outcome at discharge in a tertiary care centre Indian Journal of Endocrinology and Metabolism cardiac transplantation diabetes mellitus insulin perioperative |
| title | Perioperative glycemic control in patients who underwent cardiac transplantation and effect on the outcome at discharge in a tertiary care centre |
| title_full | Perioperative glycemic control in patients who underwent cardiac transplantation and effect on the outcome at discharge in a tertiary care centre |
| title_fullStr | Perioperative glycemic control in patients who underwent cardiac transplantation and effect on the outcome at discharge in a tertiary care centre |
| title_full_unstemmed | Perioperative glycemic control in patients who underwent cardiac transplantation and effect on the outcome at discharge in a tertiary care centre |
| title_short | Perioperative glycemic control in patients who underwent cardiac transplantation and effect on the outcome at discharge in a tertiary care centre |
| title_sort | perioperative glycemic control in patients who underwent cardiac transplantation and effect on the outcome at discharge in a tertiary care centre |
| topic | cardiac transplantation diabetes mellitus insulin perioperative |
| url | http://www.ijem.in/article.asp?issn=2230-8210;year=2020;volume=24;issue=3;spage=270;epage=274;aulast=Kumbar |
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