Biodistribution of Infused Human Umbilical Cord Blood Cells in Alzheimer's Disease-Like Murine Model

Biodistribution of Infused Human Umbilical Cord Blood Cells in Alzheimer's Disease-Like Murine Model

Human umbilical cord blood cells (HUCBCs), a prolific source of non-embryonic or adult stem cells, have emerged as effective and relatively safe immunomodulators and neuroprotectors, reducing behavioral impairment in animal models of Alzheimer's disease (AD), Parkinson's disease, amyotroph...

Full description

Bibliographic Details
Main Authors:	Jared Ehrhart Ph.D., Donna Darlington, Nicole Kuzmin-Nichols, Cyndy D. Sanberg, Darrell R. Sawmiller, Paul R. Sanberg, Jun Tan
Format:	Article
Language:	English
Published:	SAGE Publishing 2016-01-01
Series:	Cell Transplantation
Online Access:	https://doi.org/10.3727/096368915X689604

Similar Items

Human Umbilical Cord Blood-Derived Monocytes Improve Cognitive Deficits and Reduce Amyloid-β Pathology in PSAPP Mice
by: Donna Darlington, et al.
Published: (2015-11-01)

Plasma Derived from Human Umbilical Cord Blood Modulates Mitogen-Induced Proliferation of Mononuclear Cells Isolated from the Peripheral Blood of ALS Patients
by: David J. Eve, et al.
Published: (2016-05-01)

Human umbilical cord blood treatment in a mouse model of ALS: optimization of cell dose.
by: Svitlana Garbuzova-Davis, et al.
Published: (2008-06-01)

A Hallmark Clinical Study of Cord Blood Therapy in Adults with Ischemic Stroke
by: Paul R. Sanberg, et al.
Published: (2019-09-01)

Amelioration of Ischemic Brain Injury in Rats with Human Umbilical Cord Blood Stem Cells: Mechanisms of Action
by: Laura L. Hocum Stone, et al.
Published: (2016-08-01)

Human Umbilical Cord Blood Serum–derived α-Secretase
by: Ahsan Habib, et al.
Published: (2018-03-01)

Human Umbilical Cord Blood Cell Grafts for Brain Ischemia
by: Dong-Hyuk Park, et al.
Published: (2009-09-01)

Repeated Administrations of Human Umbilical Cord Blood Cells Improve Disease Outcomes in a Mouse Model of Sanfilippo Syndrome Type III B
by: Alison E. Willing Ph.D., et al.
Published: (2014-12-01)

Therapeutic Benefit of Treatment of Stroke with Simvastatin and Human Umbilical Cord Blood Cells: Neurogenesis, Synaptic Plasticity, and Axon Growth
by: Xu Cui, et al.
Published: (2012-05-01)

The Treatment of Neurodegenerative Disorders Using Umbilical Cord Blood and Menstrual Blood-Derived Stem Cells
by: Paul R. Sanberg, et al.
Published: (2011-02-01)

Cell therapy, stem cells, and brain repair /
by: Sanberg, Cyndy Davis, et al.
Published: (2006)

Umbilical Cord Blood Research: Current and Future Perspectives
by: Jennifer D. Newcomb, et al.
Published: (2007-02-01)

Timing of Cord Blood Treatment after Experimental Stroke Determines Therapeutic Efficacy
by: Jennifer D. Newcomb, et al.
Published: (2006-03-01)

Beneficial effects of a pyrroloquinolinequinone-containing dietary formulation on motor deficiency, cognitive decline and mitochondrial dysfunction in a mouse model of Alzheimer’s disease
by: Darrell Sawmiller, et al.
Published: (2017-04-01)

Book Review: Hematopoietic Stem Cell Protocol
by: Guoqing Liu, et al.
Published: (2004-07-01)

Umbilical Cord Blood Infusion Reactions
by: Rachel Hollowell, et al.
Published: (2020-09-01)

Human Umbilical Cord Blood Mononuclear Cells for the Treatment of Acute Myocardial Infarction
by: Robert J. Henning M.D., et al.
Published: (2004-10-01)

G-CSF as an Adjunctive Therapy with Umbilical Cord Blood Cell Transplantation for Traumatic Brain Injury
by: Ike De La Peña, et al.
Published: (2015-03-01)

Immunomodulation with Human Umbilical Cord Blood Stem Cells Ameliorates Ischemic Brain Injury – A Brain Transcriptome Profiling Analysis
by: Maple L. Shiao, et al.
Published: (2019-07-01)

Human Umbilical Cord Cells Express Neural Markers after Transplantation into Subventricular Zone of the DevelopingRat Brain
by: T. Zigova, et al.
Published: (2001-09-01)

Propionate and Alzheimer’s Disease
by: Jessica Killingsworth, et al.
Published: (2021-01-01)

Article Commentary: Cell Transplantation: The Regenerative Medicine Journal. A Biennial Analysis of Publications
by: Paul R. Sanberg, et al.
Published: (2003-11-01)

Enhancing endogenous stem cells in the newborn via delayed umbilical cord clamping
by: Christopher Lawton, et al.
Published: (2015-01-01)

Intravenous Administration of Human Umbilical Cord Blood Reduces Neurological Deficit in the Rat after Traumatic Brain Injury
by: Dunyue Lu, et al.
Published: (2002-04-01)

Human Umbilical Cord Blood Progenitor Cells are Attracted to Infarcted Myocardium and Significantly Reduce Myocardial Infarction Size
by: Robert J. Henning M.D., et al.
Published: (2006-08-01)

Peripheral injection of human umbilical cord blood stimulates neurogenesis in the aged rat brain
by: Sanberg Paul R, et al.
Published: (2008-02-01)

Human Umbilical Cord Blood Cells Express Neural Antigens after Transplantation into the Developing Rat Brain
by: Tanja Zigova Ph.D., et al.
Published: (2002-04-01)

Biodistribution of allogenic umbilical cord-derived mesenchymal stromal cells after fetal repair of myelomeningocele in an ovine model
by: Yoann Athiel, et al.
Published: (2022-07-01)

The Immune System as a Therapeutic Target for Alzheimer’s Disease
by: Tarek Zieneldien, et al.
Published: (2022-09-01)

Mannitol-Enhanced Delivery of Stem Cells and Their Growth Factors across the Blood–Brain Barrier
by: Gabriel S. Gonzales-Portillo, et al.
Published: (2014-05-01)

Human Umbilical Cord Blood Cells Induce Neuroprotective Change in Gene Expression Profile in Neurons after Ischemia through Activation of Akt Pathway
by: M. D. Shahaduzzaman, et al.
Published: (2015-04-01)

Human umbilical cord blood infusions in management of autism spectrum disorder: Narrative review
by: M. Adnan, et al.
Published: (2021-04-01)

Expanded Access Protocol of Umbilical Cord Blood Infusion for Children with Neurological Conditions: An Update
by: Colleen McLaughlin, et al.
Published: (2021-09-01)

Combination therapy of human umbilical cord blood cells and granulocyte colony stimulating factor reduces histopathological and motor impairments in an experimental model of chronic traumatic brain injury.
by: Sandra A Acosta, et al.
Published: (2014-01-01)

Apigenin and luteolin modulate microglial activation via inhibition of STAT1-induced CD40 expression
by: Bickford Paula, et al.
Published: (2008-09-01)

Cell Transplantation: A Forum for Discussion
by: Paul R. Sanberg
Published: (1992-03-01)

Editorial
by: Paul R. Sanberg
Published: (1994-01-01)

Cell Transplantation: Science at the Highest Level
by: Paul R. Sanberg
Published: (2016-04-01)

Geoffrey Raisman, 1939-2017: “Opening a Scientific Door and Giving Hope”
by: Paul R. Sanberg
Published: (2017-05-01)

The therapeutic potential of stem cells in umbilical cord and umbilical cord blood
by: Watt, S, et al.
Published: (2010)