Capsazepine, a Transient Receptor Potential Vanilloid Type 1 (TRPV1) Antagonist, Attenuates Antinociceptive Effect of CB1 Receptor agonist, WIN55,212-2, in the Rat Nucleus Cuneiformis

Capsazepine, a Transient Receptor Potential Vanilloid Type 1 (TRPV1) Antagonist, Attenuates Antinociceptive Effect of CB1 Receptor agonist, WIN55,212-2, in the Rat Nucleus Cuneiformis

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Introduction: Nucleus cuneiformis (NCF), as part of descending pain inhibitory system, cooperates with periaqueductal gray (PAG) and rostral ventromedial medulla (RVM) in supraspinal modulation of pain. Cannabinoids have analgesic effects in the PAG, RVM and NCF. The transient receptor potential van...

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Bibliographic Details
Main Authors: Asghar Parvishan, Zahra Taslimil, Mohammad Ebrahimzadeh, Abbas Haghparast
Format: Article
Language:English
Published: Iran University of Medical Sciences 2011-08-01
Series:Basic and Clinical Neuroscience
Subjects:
Nucleus Cuneiformis
TRPV1 Receptor
Cannabinoids
Tail-Flick
Formalin Test
Rat
Online Access:http://bcn.iums.ac.ir/browse.php?a_code=A-10-1-72&slc_lang=en&sid=1

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