A rare case of Blastomyces dermatitidis brain abscess in an immunocompetent host
Here we present a case of a 41-year old immunocompetent female from central Maryland, who presented with new onset seizures. Magnetic resonance imaging of brain revealed a solitary ring-enhancing lesion. Stereotactic brain biopsy confirmed Blastomyces dermatitidis brain abscess. Patient's clini...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2020-06-01
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| Series: | Medical Mycology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211753920300154 |
| _version_ | 1818273484983238656 |
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| author | Magdalena Slomka James Doub |
| author_facet | Magdalena Slomka James Doub |
| author_sort | Magdalena Slomka |
| collection | DOAJ |
| description | Here we present a case of a 41-year old immunocompetent female from central Maryland, who presented with new onset seizures. Magnetic resonance imaging of brain revealed a solitary ring-enhancing lesion. Stereotactic brain biopsy confirmed Blastomyces dermatitidis brain abscess. Patient's clinical course was complicated by voriconazole-induced pancytopenia that prompted surgical resection and amphothericin-induced severe hypokalemia necessitating change to high dose fluconazole. Four months after surgical resection, patient remains in radiographic and clinical remission. |
| first_indexed | 2024-12-12T21:58:42Z |
| format | Article |
| id | doaj.art-6377a2a4d0e942dca27af4d036f18512 |
| institution | Directory Open Access Journal |
| issn | 2211-7539 |
| language | English |
| last_indexed | 2024-12-12T21:58:42Z |
| publishDate | 2020-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Medical Mycology Case Reports |
| spelling | doaj.art-6377a2a4d0e942dca27af4d036f185122022-12-22T00:10:34ZengElsevierMedical Mycology Case Reports2211-75392020-06-0128811A rare case of Blastomyces dermatitidis brain abscess in an immunocompetent hostMagdalena Slomka0James Doub1Division of Infectious Diseases, University of Maryland School of Medicine, Baltimore, MD, USACorresponding author. 725 West Lombard Street, Baltimore, MD, 21201, USA.; Division of Infectious Diseases, University of Maryland School of Medicine, Baltimore, MD, USAHere we present a case of a 41-year old immunocompetent female from central Maryland, who presented with new onset seizures. Magnetic resonance imaging of brain revealed a solitary ring-enhancing lesion. Stereotactic brain biopsy confirmed Blastomyces dermatitidis brain abscess. Patient's clinical course was complicated by voriconazole-induced pancytopenia that prompted surgical resection and amphothericin-induced severe hypokalemia necessitating change to high dose fluconazole. Four months after surgical resection, patient remains in radiographic and clinical remission.http://www.sciencedirect.com/science/article/pii/S2211753920300154Blastomyces dermatitidisFungal brain abscessDimorphic fungiEndemic mycosesDrug inducedPancytopenia |
| spellingShingle | Magdalena Slomka James Doub A rare case of Blastomyces dermatitidis brain abscess in an immunocompetent host Medical Mycology Case Reports Blastomyces dermatitidis Fungal brain abscess Dimorphic fungi Endemic mycoses Drug induced Pancytopenia |
| title | A rare case of Blastomyces dermatitidis brain abscess in an immunocompetent host |
| title_full | A rare case of Blastomyces dermatitidis brain abscess in an immunocompetent host |
| title_fullStr | A rare case of Blastomyces dermatitidis brain abscess in an immunocompetent host |
| title_full_unstemmed | A rare case of Blastomyces dermatitidis brain abscess in an immunocompetent host |
| title_short | A rare case of Blastomyces dermatitidis brain abscess in an immunocompetent host |
| title_sort | rare case of blastomyces dermatitidis brain abscess in an immunocompetent host |
| topic | Blastomyces dermatitidis Fungal brain abscess Dimorphic fungi Endemic mycoses Drug induced Pancytopenia |
| url | http://www.sciencedirect.com/science/article/pii/S2211753920300154 |
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