A New Insight into the Role of CART in Cocaine Reward: Involvement of CaMKII and Inhibitory G-Protein Coupled Receptor Signaling

A New Insight into the Role of CART in Cocaine Reward: Involvement of CaMKII and Inhibitory G-Protein Coupled Receptor Signaling

Cocaine- and amphetamine-regulated transcript (CART) peptides are neuropeptides that are expressed in brain regions associated with reward, such as the nucleus accumbens (NAc), and play a role in cocaine reward. Injection of CART into the NAc can inhibit the behavioral effects of cocaine, and inject...

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Bibliographic Details
Main Authors: ChengPeng Yu, XiaoYan Zhou, Qiang Fu, QingHua Peng, Ki-Wan Oh, ZhenZhen Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Cellular Neuroscience
Subjects:
CART
cocaine addiction
CaMKII
GABABR
D3R
Online Access:http://journal.frontiersin.org/article/10.3389/fncel.2017.00244/full

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