Computational drug design of potential α-amylase inhibitors using some commercially available flavonoids

Computational drug design of potential α-amylase inhibitors using some commercially available flavonoids

The primary objective of this study was to investigate the α-amylase inhibitory activity of flavonoids using in silico docking studies. In this perspective, flavonoids like biochanin, chrysin, hesperitin, morin, tricin and vitexycarpin were selected. Acarbose, a known α-amylase inhibitor was used as...

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Bibliographic Details
Main Authors: Arumugam Madeswaran, Kuppusamy Asokkumar, Muthuswamy Umamaheswari, Thirumalaisamy Sivashanmugam, Varadharajan Subhadradevi, Puliyath Jagannath
Format: Article
Language:English
Published: Bangladesh Pharmacological Society 2014-02-01
Series:Bangladesh Journal of Pharmacology
Subjects:
Acarbose
Diabetes
Binding energy
Inhibition constant
Intermolecular energy
Online Access:https://www.banglajol.info/index.php/BJP/article/view/17502

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