Increasing the Efficiency of Emulsion Crystallization in Stirred Vessels by Targeted Application of Shear and Surfactant
Emulsions containing crystalline dispersed phases hold significant importance in pharmaceutical, chemical, and life science industries. The industrial agitation and storage of these emulsions can prompt crystallization effects within the flow field, intersecting with the primary nucleation mechanism...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-11-01
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| Series: | Colloids and Interfaces |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2504-5377/7/4/68 |
| _version_ | 1827575192141955072 |
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| author | Gina Kaysan Linda Elmlinger Matthias Kind |
| author_facet | Gina Kaysan Linda Elmlinger Matthias Kind |
| author_sort | Gina Kaysan |
| collection | DOAJ |
| description | Emulsions containing crystalline dispersed phases hold significant importance in pharmaceutical, chemical, and life science industries. The industrial agitation and storage of these emulsions can prompt crystallization effects within the flow field, intersecting with the primary nucleation mechanisms. Notably, contact-mediated nucleation, in which subcooled droplets crystallize upon contact with a crystalline particle, and shear-induced crystallization due to droplet deformation, are both conceivable phenomena. This study delves into the crystallization processes of emulsions in a 1 L stirred vessel, integrating an ultrasonic probe to monitor droplet crystallization progression. By scrutinizing the influence of the flow field and of the emulsifiers stabilizing the droplets, our investigation unveils the direct impact of enhanced rotational speed on accelerating the crystallization rate, correlating with increased energy input. Furthermore, the concentration of emulsifiers is observed to positively affect the crystallization process. Significantly, this pioneering investigation marks the first evaluation of emulsion crystallization considering the overlapping nucleation mechanisms seen in industrial production of melt emulsions. The findings offer valuable insights for more systematic control strategies in emulsion crystallization processes, promising more efficient and sustainable industrial practices by enabling targeted application of shear and surfactants. |
| first_indexed | 2024-03-08T20:52:42Z |
| format | Article |
| id | doaj.art-6388c07080cf4b6d80311ac50df44c7c |
| institution | Directory Open Access Journal |
| issn | 2504-5377 |
| language | English |
| last_indexed | 2024-03-08T20:52:42Z |
| publishDate | 2023-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Colloids and Interfaces |
| spelling | doaj.art-6388c07080cf4b6d80311ac50df44c7c2023-12-22T14:01:10ZengMDPI AGColloids and Interfaces2504-53772023-11-01746810.3390/colloids7040068Increasing the Efficiency of Emulsion Crystallization in Stirred Vessels by Targeted Application of Shear and SurfactantGina Kaysan0Linda Elmlinger1Matthias Kind2Institute for Thermal Process Engineering, Karlsruhe Institute of Technology, 76131 Karlsruhe, GermanyInstitute for Thermal Process Engineering, Karlsruhe Institute of Technology, 76131 Karlsruhe, GermanyInstitute for Thermal Process Engineering, Karlsruhe Institute of Technology, 76131 Karlsruhe, GermanyEmulsions containing crystalline dispersed phases hold significant importance in pharmaceutical, chemical, and life science industries. The industrial agitation and storage of these emulsions can prompt crystallization effects within the flow field, intersecting with the primary nucleation mechanisms. Notably, contact-mediated nucleation, in which subcooled droplets crystallize upon contact with a crystalline particle, and shear-induced crystallization due to droplet deformation, are both conceivable phenomena. This study delves into the crystallization processes of emulsions in a 1 L stirred vessel, integrating an ultrasonic probe to monitor droplet crystallization progression. By scrutinizing the influence of the flow field and of the emulsifiers stabilizing the droplets, our investigation unveils the direct impact of enhanced rotational speed on accelerating the crystallization rate, correlating with increased energy input. Furthermore, the concentration of emulsifiers is observed to positively affect the crystallization process. Significantly, this pioneering investigation marks the first evaluation of emulsion crystallization considering the overlapping nucleation mechanisms seen in industrial production of melt emulsions. The findings offer valuable insights for more systematic control strategies in emulsion crystallization processes, promising more efficient and sustainable industrial practices by enabling targeted application of shear and surfactants.https://www.mdpi.com/2504-5377/7/4/68crystallizationemulsiondropletparticlecontact-mediated nucleationshear-induced nucleation |
| spellingShingle | Gina Kaysan Linda Elmlinger Matthias Kind Increasing the Efficiency of Emulsion Crystallization in Stirred Vessels by Targeted Application of Shear and Surfactant Colloids and Interfaces crystallization emulsion droplet particle contact-mediated nucleation shear-induced nucleation |
| title | Increasing the Efficiency of Emulsion Crystallization in Stirred Vessels by Targeted Application of Shear and Surfactant |
| title_full | Increasing the Efficiency of Emulsion Crystallization in Stirred Vessels by Targeted Application of Shear and Surfactant |
| title_fullStr | Increasing the Efficiency of Emulsion Crystallization in Stirred Vessels by Targeted Application of Shear and Surfactant |
| title_full_unstemmed | Increasing the Efficiency of Emulsion Crystallization in Stirred Vessels by Targeted Application of Shear and Surfactant |
| title_short | Increasing the Efficiency of Emulsion Crystallization in Stirred Vessels by Targeted Application of Shear and Surfactant |
| title_sort | increasing the efficiency of emulsion crystallization in stirred vessels by targeted application of shear and surfactant |
| topic | crystallization emulsion droplet particle contact-mediated nucleation shear-induced nucleation |
| url | https://www.mdpi.com/2504-5377/7/4/68 |
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