Annular and supra-annular structure assessments for transcatheter aortic valve replacement in patients with bicuspid aortic stenosis

The clinical use indications for transcatheter aortic valve replacement (TAVR) for the treatment of severe symptomatic aortic stenosis (AS) have expanded from patients at high surgical risk to those at low risk based on the results of multiple large-scale randomized trials. However, patients with...

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Main Authors: Jian-Di Liu, Xian-Du Luo, Zhi-Peng Zhou, Ren Gong, Yan-Qing Wu
Format: Article
Language:English
Published: IMR Press 2021-12-01
Series:Reviews in Cardiovascular Medicine
Subjects:
Online Access:https://rcm.imrpress.com/EN/10.31083/j.rcm2204124
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author Jian-Di Liu
Xian-Du Luo
Zhi-Peng Zhou
Ren Gong
Yan-Qing Wu
author_facet Jian-Di Liu
Xian-Du Luo
Zhi-Peng Zhou
Ren Gong
Yan-Qing Wu
author_sort Jian-Di Liu
collection DOAJ
description The clinical use indications for transcatheter aortic valve replacement (TAVR) for the treatment of severe symptomatic aortic stenosis (AS) have expanded from patients at high surgical risk to those at low risk based on the results of multiple large-scale randomized trials. However, patients with bicuspid AS have traditionally been excluded from clinical trials due to their unfavorable morphological characteristics. Bicuspid aortic valve (BAV) is the most frequent congenital heart disease, occurring in 1% to 2% of the total population and affects more than 20% of octogenarians undergoing isolated aortic valve replacement for AS. In recent years, TAVR in patients with bicuspid AS has been the focus of research, especially with respect to the standard of prosthesis size selection. Annulus-based prosthesis size selection using computed tomography (CT) is the standard sizing strategy for tricuspid AS, but no standard sizing for bicuspid AS has been developed thus far. According to Western TAVR experiences, transcatheter heart valve (THV) size selection for BAV patients should be based on the annular structure assessment by CT measurement, whereas Chinese experiences favor adopting the supra-annulus structure assessment for THV size selection. This article will review annular and supra-annular sizing for prosthesis size selection in patients with bicuspid AS before TAVR and discuss which has more favorable clinical outcomes.
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spelling doaj.art-6389b63aa1794786a1a6c844083727e72022-12-21T18:41:52ZengIMR PressReviews in Cardiovascular Medicine2153-81742021-12-012241157116610.31083/j.rcm2204124S1530-6550(21)00244-1Annular and supra-annular structure assessments for transcatheter aortic valve replacement in patients with bicuspid aortic stenosisJian-Di Liu0Xian-Du Luo1Zhi-Peng Zhou2Ren Gong3Yan-Qing Wu4Department of Cardiology, The Second Affiliated Hospital of Nanchang University, 330006 Nanchang, Jiangxi, ChinaDepartment of Cardiology, The Second Affiliated Hospital of Nanchang University, 330006 Nanchang, Jiangxi, ChinaDepartment of Cardiology, The Second Affiliated Hospital of Nanchang University, 330006 Nanchang, Jiangxi, ChinaDepartment of Cardiology, The Second Affiliated Hospital of Nanchang University, 330006 Nanchang, Jiangxi, ChinaDepartment of Cardiology, The Second Affiliated Hospital of Nanchang University, 330006 Nanchang, Jiangxi, ChinaThe clinical use indications for transcatheter aortic valve replacement (TAVR) for the treatment of severe symptomatic aortic stenosis (AS) have expanded from patients at high surgical risk to those at low risk based on the results of multiple large-scale randomized trials. However, patients with bicuspid AS have traditionally been excluded from clinical trials due to their unfavorable morphological characteristics. Bicuspid aortic valve (BAV) is the most frequent congenital heart disease, occurring in 1% to 2% of the total population and affects more than 20% of octogenarians undergoing isolated aortic valve replacement for AS. In recent years, TAVR in patients with bicuspid AS has been the focus of research, especially with respect to the standard of prosthesis size selection. Annulus-based prosthesis size selection using computed tomography (CT) is the standard sizing strategy for tricuspid AS, but no standard sizing for bicuspid AS has been developed thus far. According to Western TAVR experiences, transcatheter heart valve (THV) size selection for BAV patients should be based on the annular structure assessment by CT measurement, whereas Chinese experiences favor adopting the supra-annulus structure assessment for THV size selection. This article will review annular and supra-annular sizing for prosthesis size selection in patients with bicuspid AS before TAVR and discuss which has more favorable clinical outcomes.https://rcm.imrpress.com/EN/10.31083/j.rcm2204124transcatheter aortic valve replacement (tavr)aortic stenosis (as)bicuspid aortic valve (bav)prosthesis size selection
spellingShingle Jian-Di Liu
Xian-Du Luo
Zhi-Peng Zhou
Ren Gong
Yan-Qing Wu
Annular and supra-annular structure assessments for transcatheter aortic valve replacement in patients with bicuspid aortic stenosis
Reviews in Cardiovascular Medicine
transcatheter aortic valve replacement (tavr)
aortic stenosis (as)
bicuspid aortic valve (bav)
prosthesis size selection
title Annular and supra-annular structure assessments for transcatheter aortic valve replacement in patients with bicuspid aortic stenosis
title_full Annular and supra-annular structure assessments for transcatheter aortic valve replacement in patients with bicuspid aortic stenosis
title_fullStr Annular and supra-annular structure assessments for transcatheter aortic valve replacement in patients with bicuspid aortic stenosis
title_full_unstemmed Annular and supra-annular structure assessments for transcatheter aortic valve replacement in patients with bicuspid aortic stenosis
title_short Annular and supra-annular structure assessments for transcatheter aortic valve replacement in patients with bicuspid aortic stenosis
title_sort annular and supra annular structure assessments for transcatheter aortic valve replacement in patients with bicuspid aortic stenosis
topic transcatheter aortic valve replacement (tavr)
aortic stenosis (as)
bicuspid aortic valve (bav)
prosthesis size selection
url https://rcm.imrpress.com/EN/10.31083/j.rcm2204124
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