Direct Enhancement Effect of Hippocampal Cholinergic Neurostimulating Peptide on Cholinergic Activity in the Hippocampus

Direct Enhancement Effect of Hippocampal Cholinergic Neurostimulating Peptide on Cholinergic Activity in the Hippocampus

The cholinergic efferent network from the medial septal nucleus to the hippocampus is crucial for learning and memory. This study aimed to clarify whether hippocampal cholinergic neurostimulating peptide (HCNP) has a rescue function in the cholinergic dysfunction of HCNP precursor protein (HCNP-pp)...

Full description

Bibliographic Details
Main Authors:	Yuta Madokoro, Daisuke Kato, Yo Tsuda, Itsumi Arakawa, Kengo Suzuki, Toyohiro Sato, Masayuki Mizuno, Yuto Uchida, Kosei Ojika, Noriyuki Matsukawa
Format:	Article
Language:	English
Published:	MDPI AG 2023-05-01
Series:	International Journal of Molecular Sciences
Subjects:	hippocampal cholinergic neurostimulating peptide hippocampal cholinergic neurostimulating peptide precursor protein hippocampal HCNP-pp conditional KO mouse model choline acetyltransferase local field potential theta oscillation
Online Access:	https://www.mdpi.com/1422-0067/24/10/8916

Similar Items

Cholinergic REST-G9a gene repression through HMGB1-TLR4 neuroimmune signaling regulates basal forebrain cholinergic neuron phenotype
by: Fulton T. Crews, et al.
Published: (2022-08-01)

The Cholinergic System Modulates Memory and Hippocampal Plasticity via Its Interactions with Non-Neuronal Cells
by: Sara V. Maurer, et al.
Published: (2017-11-01)

Central Cholinergic Nervous System and Cholinergic Agents
by: Jiří Patočka
Published: (1998-01-01)

Cholinergic Machinery as Relevant Target in Acute Lymphoblastic T Leukemia
by: Oxana Dobrovinskaya, et al.
Published: (2016-08-01)

Accuracy and Workflow Improvements for Responsive Neurostimulation Hippocampal Depth Electrode Placement Using Robotic Stereotaxy
by: Patrick J. Karas, et al.
Published: (2020-12-01)

Expression of Cholinergic Markers and Characterization of Splice Variants during Ontogenesis of Rat Dorsal Root Ganglia Neurons
by: Veronica Corsetti, et al.
Published: (2021-05-01)

Increased Endogenous GDNF in Mice Protects Against Age-Related Decline in Neuronal Cholinergic Markers
by: Sumonto Mitra, et al.
Published: (2021-08-01)

Activation of medial septum cholinergic neurons restores cognitive function in temporal lobe epilepsy
by: Junzi Chen, et al.
Published: (2023-01-01)

Current understanding of neurostimulation for Parkinson's disease
by: Ekaterina V. Bril, et al.
Published: (2022-06-01)

Pediatric Toxidrome Simulation Curriculum: Cholinergic Toxidrome
by: Jennifer Reid, et al.
Published: (2012-03-01)

New insight on the enteric cholinergic innervation of the pig colon by central and peripheral nervous systems: reduction by repeated loperamide administration
by: Pu-Qing Yuan, et al.
Published: (2023-08-01)

Reduction of glutamatergic activity through cholinergic dysfunction in the hippocampus of hippocampal cholinergic neurostimulating peptide precursor protein knockout mice
by: Kengo Suzuki, et al.
Published: (2022-11-01)

Cholinergic Polarization of Human Macrophages
by: Natalia Roa-Vidal, et al.
Published: (2023-10-01)

THE IMPORTANCE OF CENTRAL CHOLINERGIC SYSTEMS ACTIVATION IN TRAUMATIC BRAIN INJURY
by: S.V. Ziablitsev, et al.
Published: (2020-09-01)

The Theta Rhythm of the Hippocampus: From Neuronal and Circuit Mechanisms to Behavior
by: Angel Nuñez, et al.
Published: (2021-03-01)

Caffeine Compromises Proliferation of Human Hippocampal Progenitor Cells
by: Vikki Houghton, et al.
Published: (2020-09-01)

CSF and Plasma Cholinergic Markers in Patients With Cognitive Impairment
by: Azadeh Karami, et al.
Published: (2021-08-01)

Effects of repetitive transcranial magnetic stimulation on cognitive function and cholinergic activity in the rat hippocampus after vascular dementia
by: Xiao-Qiao Zhang, et al.
Published: (2018-01-01)

Choline kinase alpha genotype is related to hippocampal brain volume and cognition in postmenopausal women
by: Abigail J. Myers, et al.
Published: (2024-01-01)

A Novel Antiserum Against a Predicted Human Peripheral Choline Acetyltransferase (hpChAT) for Labeling Neuronal Structures in Human Colon
by: Jean-Pierre Bellier, et al.
Published: (2019-04-01)

Cholinergic System and Its Therapeutic Importance in Inflammation and Autoimmunity
by: Namrita Halder, et al.
Published: (2021-04-01)

Change in hippocampal theta activity with transfer from simple discrimination tasks to a simultaneous feature-negative task
by: Yuya eSakimoto, et al.
Published: (2014-06-01)

Hippocampal Malrotation: A Genetic Developmental Anomaly Related to Epilepsy?
by: Ting-Ying Fu, et al.
Published: (2021-04-01)

Exploring the vertebrate cholinergic nervous system /
by: Karczmar, A. G. (Alexander George), 1918-, et al.
Published: (2007)

A Hippocampal Model for Behavioral Time Acquisition and Fast Bidirectional Replay of Spatio-Temporal Memory Sequences
by: Marcelo Matheus Gauy, et al.
Published: (2018-12-01)

Extrinsic sources of cholinergic innervation of the striatal complex: a whole-brain mapping analysis
by: Daniel eDautan, et al.
Published: (2016-01-01)

Rewiring of Memory Circuits: Connecting Adult Newborn Neurons With the Help of Microglia
by: Noelia Rodríguez-Iglesias, et al.
Published: (2019-03-01)

Cyclosporine in cholinergic itch
by: Sumit Sehgal, et al.
Published: (2022-01-01)

Opposite Pathways of Cholinergic Mechanisms of Hypoxic Preconditioning in the Hippocampus: Participation of Nicotinic α7 Receptors and Their Association with the Baseline Level of Startle Prepulse Inhibition
by: Elena I. Zakharova, et al.
Published: (2020-12-01)

Cholinergic Signaling, Neural Excitability, and Epilepsy
by: Yu Wang, et al.
Published: (2021-04-01)

Allosteric Binding Sites of Aβ Peptides on the Acetylcholine Synthesizing Enzyme ChAT as Deduced by In Silico Molecular Modeling
by: Anurag TK Baidya, et al.
Published: (2022-05-01)

Peripheral Nerve Impairment in a Mouse Model of Alzheimer’s Disease
by: Alessio Torcinaro, et al.
Published: (2021-09-01)

Older rats show slow modulation of hippocampal theta rhythm during voluntary running
by: Cheryl C.H. Yang, et al.
Published: (2023-03-01)

Specific Increase of Hippocampal Delta Oscillations Across Consecutive Treadmill Runs
by: Alan M. B. Furtunato, et al.
Published: (2020-06-01)

Human cerebrospinal fluid promotes neuronal viability and activity of hippocampal neuronal circuits in vitro
by: Marta ePerez-Alcazar, et al.
Published: (2016-03-01)

Cellular birthdate predicts laminar and regional cholinergic projection topography in the forebrain
by: Kathryn C Allaway, et al.
Published: (2020-12-01)

A handbook for modeling hippocampal circuits
by: Michael E Hasselmo
Published: (2011-01-01)

Prevalence of hippocampal morphologic variants between healthy elderly subjects and patients with Alzheimer′s disease
by: Ali Hekmatnia, et al.
Published: (2014-01-01)

Effects of Aging on the Volume of Hippocampal Subdivisions in Rat
by: J Hosseinzadeh, et al.
Published: (2011-05-01)

An invertebrate-specific miRNA targeted the ancient cholinergic neuroendocrine system of oyster
by: Hao Chen, et al.
Published: (2016-01-01)