Underlying Primary Causes of Chronic Renal Failure: A Three-Year Study in Al-Thawra General Hospital, Sana'a, Yemen

Objective: To estimate the underlying primary diseases of chronic renal failure (CRF) among patients attending Al-Thawra General Hospital, Sana'a, and Yemen. Methods: This was a cross-sectional, hospital-based study of 566 patients diagnosed with chronic kidney diseases (CKD). It studied the c...

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Main Authors: Mogahid Y. Nassar, Hassan A. Al-Shamahy, Abdullah S. Al-Samawi, Nagieb W. Abu Asba, Ibrahiem H. El-Nono, Haitham A. Masood
Format: Article
Language:English
Published: University of Science and Technology, Yemen 2016-05-01
Series:Yemeni Journal for Medical Sciences
Subjects:
Online Access:https://journals.ust.edu/index.php/yjms/article/view/958
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author Mogahid Y. Nassar
Hassan A. Al-Shamahy
Abdullah S. Al-Samawi
Nagieb W. Abu Asba
Ibrahiem H. El-Nono
Haitham A. Masood
author_facet Mogahid Y. Nassar
Hassan A. Al-Shamahy
Abdullah S. Al-Samawi
Nagieb W. Abu Asba
Ibrahiem H. El-Nono
Haitham A. Masood
author_sort Mogahid Y. Nassar
collection DOAJ
description Objective: To estimate the underlying primary diseases of chronic renal failure (CRF) among patients attending Al-Thawra General Hospital, Sana'a, and Yemen. Methods: This was a cross-sectional, hospital-based study of 566 patients diagnosed with chronic kidney diseases (CKD). It studied the cases attending Al-Thawra General Hospital over a three‐year period from January 2013 to December 2015. Results: Out of 566 patients, 339 (59.9%) were males. The mean age of the patients at diagnosis of CKD was 39.51 years, most of whom (36.6%) were of the age group of 21–35 years. Hypertension was the most frequent cause (43.2%) of CRF, followed by different infectious diseases such as malaria, schistosomiasis and bacterial infections (19%) and obstructive nephropathy (17.9%). On the other hand, CRF of unknown etiology represented 15.2% of cases. Other causes of CRF diabetic nephropathy (9.7%), effect of antibiotics and analgesics (7.0%), ischemic heart disease (4.8%, polycystic kidney disease (3.5%) and congenital anomalies (3.4%). The least common causes were autoimmune diseases, bleeding, traumatic accidents and chronic diarrhea, being responsible for 2.2%, 1.8%, 0.9% and 0.4% of CRF cases, respectively. Conclusions: The majority of CKD cases in our study were males aged between 21 and 35 years old. In addition, most cases of CKD are due to hypertension, followed by infections and obstructive nephropathy. Application of future prevention and control measures are highly recommended to reduce the burden of CRF in Yemen for early detection and proper management of its underlying primary conditions/diseases.
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spelling doaj.art-638b2addec1e4018a05c6818ea1d86052022-12-22T00:32:05ZengUniversity of Science and Technology, YemenYemeni Journal for Medical Sciences2227-96012227-961X2016-05-01101242910.20428/YJMS.10.1.4886Underlying Primary Causes of Chronic Renal Failure: A Three-Year Study in Al-Thawra General Hospital, Sana'a, YemenMogahid Y. Nassar0Hassan A. Al-Shamahy1Abdullah S. Al-Samawi2Nagieb W. Abu Asba3Ibrahiem H. El-Nono4Haitham A. Masood5Department of Clinical Pathology, Faculty of Medicine and Health Sciences, University of Science and Technology, Sana'aDepartment of Microbiology, Faculty of Medicine and Health Sciences, Sana'a University, Sana'aDepartment of Pathology, Faculty of Medicine and Health Sciences, Sana'a University, Sana'aUrology and Nephrology Center, Al-Thawra General Hospital; Department of Nephrology, Faculty of Medicine and Health Sciences, Sana'a University, Sana'aUrology and Nephrology Center Al-Thawra General Hospital; Department of Urology, Faculty of Medicine and Health Sciences, Sana'a University, Sana'aHLA Typing Unit, Al-Thawra General Hospital, Sana'aObjective: To estimate the underlying primary diseases of chronic renal failure (CRF) among patients attending Al-Thawra General Hospital, Sana'a, and Yemen. Methods: This was a cross-sectional, hospital-based study of 566 patients diagnosed with chronic kidney diseases (CKD). It studied the cases attending Al-Thawra General Hospital over a three‐year period from January 2013 to December 2015. Results: Out of 566 patients, 339 (59.9%) were males. The mean age of the patients at diagnosis of CKD was 39.51 years, most of whom (36.6%) were of the age group of 21–35 years. Hypertension was the most frequent cause (43.2%) of CRF, followed by different infectious diseases such as malaria, schistosomiasis and bacterial infections (19%) and obstructive nephropathy (17.9%). On the other hand, CRF of unknown etiology represented 15.2% of cases. Other causes of CRF diabetic nephropathy (9.7%), effect of antibiotics and analgesics (7.0%), ischemic heart disease (4.8%, polycystic kidney disease (3.5%) and congenital anomalies (3.4%). The least common causes were autoimmune diseases, bleeding, traumatic accidents and chronic diarrhea, being responsible for 2.2%, 1.8%, 0.9% and 0.4% of CRF cases, respectively. Conclusions: The majority of CKD cases in our study were males aged between 21 and 35 years old. In addition, most cases of CKD are due to hypertension, followed by infections and obstructive nephropathy. Application of future prevention and control measures are highly recommended to reduce the burden of CRF in Yemen for early detection and proper management of its underlying primary conditions/diseases.https://journals.ust.edu/index.php/yjms/article/view/958chronic renal failureprimary diseasesana'ayemen
spellingShingle Mogahid Y. Nassar
Hassan A. Al-Shamahy
Abdullah S. Al-Samawi
Nagieb W. Abu Asba
Ibrahiem H. El-Nono
Haitham A. Masood
Underlying Primary Causes of Chronic Renal Failure: A Three-Year Study in Al-Thawra General Hospital, Sana'a, Yemen
Yemeni Journal for Medical Sciences
chronic renal failure
primary disease
sana'a
yemen
title Underlying Primary Causes of Chronic Renal Failure: A Three-Year Study in Al-Thawra General Hospital, Sana'a, Yemen
title_full Underlying Primary Causes of Chronic Renal Failure: A Three-Year Study in Al-Thawra General Hospital, Sana'a, Yemen
title_fullStr Underlying Primary Causes of Chronic Renal Failure: A Three-Year Study in Al-Thawra General Hospital, Sana'a, Yemen
title_full_unstemmed Underlying Primary Causes of Chronic Renal Failure: A Three-Year Study in Al-Thawra General Hospital, Sana'a, Yemen
title_short Underlying Primary Causes of Chronic Renal Failure: A Three-Year Study in Al-Thawra General Hospital, Sana'a, Yemen
title_sort underlying primary causes of chronic renal failure a three year study in al thawra general hospital sana a yemen
topic chronic renal failure
primary disease
sana'a
yemen
url https://journals.ust.edu/index.php/yjms/article/view/958
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