A rare association: Obesity hypoventilation syndrome with myasthenia gravis and systemic lupus erythematosus, case report
Background: Shrinking lung syndrome (SLS) is an uncommon complication of systemic lupus erythematosus (SLE) that has also been seen in other autoimmune diseases and is linked with a high risk of acute or chronic respiratory failure. Alveolar hypoventilation in the presence of obesity-hypoventilation...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-01-01
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| Series: | Respiratory Medicine Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213007123000436 |
| _version_ | 1797802850160476160 |
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| author | Safwat Eldaabossi Man Alrashdan Ghada Aljanobi Noha Warsha Saber Abo Elhassan Waheed Mahdi Abdullah Farouk Ahmad Taha Ahmad Qabil Sameh Maklad Usama Nabway Hatem Kenany Yasser Jaber Boshra Zaghloul |
| author_facet | Safwat Eldaabossi Man Alrashdan Ghada Aljanobi Noha Warsha Saber Abo Elhassan Waheed Mahdi Abdullah Farouk Ahmad Taha Ahmad Qabil Sameh Maklad Usama Nabway Hatem Kenany Yasser Jaber Boshra Zaghloul |
| author_sort | Safwat Eldaabossi |
| collection | DOAJ |
| description | Background: Shrinking lung syndrome (SLS) is an uncommon complication of systemic lupus erythematosus (SLE) that has also been seen in other autoimmune diseases and is linked with a high risk of acute or chronic respiratory failure. Alveolar hypoventilation in the presence of obesity-hypoventilation syndrome, systemic lupus erythematosus (SLE), and myasthenia gravis (MG) is uncommon and poses a diagnostic and therapeutic challenge. Case report: We reported a 33-year-old female patient from Saudi Arabia who suffered from obesity, bronchial asthma, newly diagnosed essential hypertension, type 2 diabetes mellitus, with recurrent acute alveolar hypoventilation, secondary to obesity hypoventilation syndrome and mixed autoimmune disease (systemic lupus erythematosus and myasthenia gravis), based on the correct constellation of clinical findings and laboratory evidence. Conclusion: The interesting aspect of this case report: is the presentation of the overlap of obesity hypoventilation syndrome and shrinking lung syndrome due to systemic lupus erythematosus with generalized and respiratory muscle dysfunction due to myasthenia gravis with good outcomes after therapy. |
| first_indexed | 2024-03-13T05:12:00Z |
| format | Article |
| id | doaj.art-638cae4c80d14c39aad69d3bc81f4f5e |
| institution | Directory Open Access Journal |
| issn | 2213-0071 |
| language | English |
| last_indexed | 2024-03-13T05:12:00Z |
| publishDate | 2023-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Respiratory Medicine Case Reports |
| spelling | doaj.art-638cae4c80d14c39aad69d3bc81f4f5e2023-06-16T05:09:36ZengElsevierRespiratory Medicine Case Reports2213-00712023-01-0144101848A rare association: Obesity hypoventilation syndrome with myasthenia gravis and systemic lupus erythematosus, case reportSafwat Eldaabossi0Man Alrashdan1Ghada Aljanobi2Noha Warsha3Saber Abo Elhassan4Waheed Mahdi5Abdullah Farouk6Ahmad Taha7Ahmad Qabil8Sameh Maklad9Usama Nabway10Hatem Kenany11Yasser Jaber12Boshra Zaghloul13Pulmonology Consultant, Almoosa Specialist Hospital, Al Ahsa, Saudi Arabia; Department of Chest Diseases, Al Azhar University Faculty of Medicine, Egypt; Corresponding author. Pulmonology Consultant, Almoosa Specialist Hospital, Al Ahsa, Saudi Arabia.Department of Chest Diseases, Al Azhar University Faculty of Medicine, EgyptRheumatology Consultant, Almoosa Specialist Hospital, Al Ahsa, Saudi ArabiaRheumatology Consultant, Almoosa Specialist Hospital, Al Ahsa, Saudi ArabiaNeurology Consultant, Almoosa Specialist Hospital, Al Ahsa, Saudi Arabia; Department of Neurology, Assuit Faculty of Medicine, EgyptCritical Care and Pulmonary Consultant, Almoosa Specialist Hospital, Al Ahsa, Saudi Arabia; Department of Chest diseases, Banha Faculty of Medicine, EgyptCritical Care Consultant, Almoosa Specialist Hospital, Al Ahsa, Saudi Arabia; Department of Critical Care, Alexandria Faculty of Medicine, EgyptPulmonology Consultant, Almoosa Specialist Hospital, Al Ahsa, Saudi ArabiaPulmonology Consultant, Almoosa Specialist Hospital, Al Ahsa, Saudi ArabiaPulmonology Consultant, Almoosa Specialist Hospital, Al Ahsa, Saudi ArabiaPulmonology Consultant, Almoosa Specialist Hospital, Al Ahsa, Saudi ArabiaConsultant Critical Care and Anesthesia, Al Azhar University Faculty of Medicine, EgyptRadiology Consultant, Almoosa Specialist Hospital, Al Ahsa, Saudi Arabia; Department of Radiology, Al Azhar University Faculty of Medicine, EgyptDepartment of Radiology, Al Azhar University Faculty of Medicine for Girls, EgyptBackground: Shrinking lung syndrome (SLS) is an uncommon complication of systemic lupus erythematosus (SLE) that has also been seen in other autoimmune diseases and is linked with a high risk of acute or chronic respiratory failure. Alveolar hypoventilation in the presence of obesity-hypoventilation syndrome, systemic lupus erythematosus (SLE), and myasthenia gravis (MG) is uncommon and poses a diagnostic and therapeutic challenge. Case report: We reported a 33-year-old female patient from Saudi Arabia who suffered from obesity, bronchial asthma, newly diagnosed essential hypertension, type 2 diabetes mellitus, with recurrent acute alveolar hypoventilation, secondary to obesity hypoventilation syndrome and mixed autoimmune disease (systemic lupus erythematosus and myasthenia gravis), based on the correct constellation of clinical findings and laboratory evidence. Conclusion: The interesting aspect of this case report: is the presentation of the overlap of obesity hypoventilation syndrome and shrinking lung syndrome due to systemic lupus erythematosus with generalized and respiratory muscle dysfunction due to myasthenia gravis with good outcomes after therapy.http://www.sciencedirect.com/science/article/pii/S2213007123000436Obesity hypoventilation syndromeSystemic lupus erythematosusMyasthenia gravisAlveolar hypoventilationDiaphragmShrinking lung syndrome |
| spellingShingle | Safwat Eldaabossi Man Alrashdan Ghada Aljanobi Noha Warsha Saber Abo Elhassan Waheed Mahdi Abdullah Farouk Ahmad Taha Ahmad Qabil Sameh Maklad Usama Nabway Hatem Kenany Yasser Jaber Boshra Zaghloul A rare association: Obesity hypoventilation syndrome with myasthenia gravis and systemic lupus erythematosus, case report Respiratory Medicine Case Reports Obesity hypoventilation syndrome Systemic lupus erythematosus Myasthenia gravis Alveolar hypoventilation Diaphragm Shrinking lung syndrome |
| title | A rare association: Obesity hypoventilation syndrome with myasthenia gravis and systemic lupus erythematosus, case report |
| title_full | A rare association: Obesity hypoventilation syndrome with myasthenia gravis and systemic lupus erythematosus, case report |
| title_fullStr | A rare association: Obesity hypoventilation syndrome with myasthenia gravis and systemic lupus erythematosus, case report |
| title_full_unstemmed | A rare association: Obesity hypoventilation syndrome with myasthenia gravis and systemic lupus erythematosus, case report |
| title_short | A rare association: Obesity hypoventilation syndrome with myasthenia gravis and systemic lupus erythematosus, case report |
| title_sort | rare association obesity hypoventilation syndrome with myasthenia gravis and systemic lupus erythematosus case report |
| topic | Obesity hypoventilation syndrome Systemic lupus erythematosus Myasthenia gravis Alveolar hypoventilation Diaphragm Shrinking lung syndrome |
| url | http://www.sciencedirect.com/science/article/pii/S2213007123000436 |
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