Cytogenetic Prenatal Diagnosis in the Province of Cienfuegos between 2007 and 2010
<strong>Background:</strong> cytogenetic prenatal diagnosis is nowadays part of the care provided in developed countries to high-risk pregnant women and is an indispensable component of preventive genetic programs driven by the World Health Organization.<br /> <strong>Objecti...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | Spanish |
| Published: |
Centro Provincial de Información de Ciencias Médicas. Cienfuegos
2012-11-01
|
| Series: | Medisur |
| Subjects: | |
| Online Access: | http://medisur.sld.cu/index.php/medisur/article/view/1992 |
| _version_ | 1797277993822846976 |
|---|---|
| author | Pedro Alí Díaz-Véliz Jiménez Yamelis Garrido Martínez Aime Guerra Jorge Belkis Vidal Hernández |
| author_facet | Pedro Alí Díaz-Véliz Jiménez Yamelis Garrido Martínez Aime Guerra Jorge Belkis Vidal Hernández |
| author_sort | Pedro Alí Díaz-Véliz Jiménez |
| collection | DOAJ |
| description | <strong>Background:</strong> cytogenetic prenatal diagnosis is nowadays part of the care provided in developed countries to high-risk pregnant women and is an indispensable component of preventive genetic programs driven by the World Health Organization.<br /> <strong>Objective: </strong>To present the results of cytogenetic prenatal diagnosis in the province of Cienfuegos.<br /> <strong>Methods:</strong> A chronological series study was developed at the Provincial Center of Medical Genetics of Cienfuegos on all cytogenetic prenatal diagnoses that were performed between 2007 and 2010. We analyzed causes of study, number of diagnoses and types of anomalies detected. <br /> <strong>Results:</strong> during the period analyzed, 1172 amniocentesis of pregnant patients were processed and 1076 of them were diagnosed for 91, 81 % efficiency. 85,5 % of the cases studied were women over 37 years old. 32 chromosomal abnormalities were detected. The order of frequency of chromosomal abnormalities among the positive cases was: numerical aberrations (65, 63 %), structural aberrations (18, 75 %) and mosaics (15,63 %). The most common chromosomal abnormality was Down syndrome with 46,88 % of total aberrations detected. <br /><strong>Conclusions:</strong> the indicators analyzed behave similarly to those reported in literature both from our country or international. |
| first_indexed | 2024-03-07T15:57:07Z |
| format | Article |
| id | doaj.art-638cf619f95d4d43af59817cae647c2e |
| institution | Directory Open Access Journal |
| issn | 1727-897X |
| language | Spanish |
| last_indexed | 2024-03-07T15:57:07Z |
| publishDate | 2012-11-01 |
| publisher | Centro Provincial de Información de Ciencias Médicas. Cienfuegos |
| record_format | Article |
| series | Medisur |
| spelling | doaj.art-638cf619f95d4d43af59817cae647c2e2024-03-04T23:09:41ZspaCentro Provincial de Información de Ciencias Médicas. CienfuegosMedisur1727-897X2012-11-01105399404924Cytogenetic Prenatal Diagnosis in the Province of Cienfuegos between 2007 and 2010Pedro Alí Díaz-Véliz Jiménez0Yamelis Garrido Martínez1Aime Guerra Jorge2Belkis Vidal Hernández3Centro Provincial de Genética Médica. Cienfuegos.Centro Provincial de Genética Médica. Cienfuegos.Centro Provincial de Genética Médica. Cienfuegos.Centro Provincial de Genética Médica. Cienfuegos.<strong>Background:</strong> cytogenetic prenatal diagnosis is nowadays part of the care provided in developed countries to high-risk pregnant women and is an indispensable component of preventive genetic programs driven by the World Health Organization.<br /> <strong>Objective: </strong>To present the results of cytogenetic prenatal diagnosis in the province of Cienfuegos.<br /> <strong>Methods:</strong> A chronological series study was developed at the Provincial Center of Medical Genetics of Cienfuegos on all cytogenetic prenatal diagnoses that were performed between 2007 and 2010. We analyzed causes of study, number of diagnoses and types of anomalies detected. <br /> <strong>Results:</strong> during the period analyzed, 1172 amniocentesis of pregnant patients were processed and 1076 of them were diagnosed for 91, 81 % efficiency. 85,5 % of the cases studied were women over 37 years old. 32 chromosomal abnormalities were detected. The order of frequency of chromosomal abnormalities among the positive cases was: numerical aberrations (65, 63 %), structural aberrations (18, 75 %) and mosaics (15,63 %). The most common chromosomal abnormality was Down syndrome with 46,88 % of total aberrations detected. <br /><strong>Conclusions:</strong> the indicators analyzed behave similarly to those reported in literature both from our country or international.http://medisur.sld.cu/index.php/medisur/article/view/1992diagnóstico prenatalanálisis citogenético |
| spellingShingle | Pedro Alí Díaz-Véliz Jiménez Yamelis Garrido Martínez Aime Guerra Jorge Belkis Vidal Hernández Cytogenetic Prenatal Diagnosis in the Province of Cienfuegos between 2007 and 2010 Medisur diagnóstico prenatal análisis citogenético |
| title | Cytogenetic Prenatal Diagnosis in the Province of Cienfuegos between 2007 and 2010 |
| title_full | Cytogenetic Prenatal Diagnosis in the Province of Cienfuegos between 2007 and 2010 |
| title_fullStr | Cytogenetic Prenatal Diagnosis in the Province of Cienfuegos between 2007 and 2010 |
| title_full_unstemmed | Cytogenetic Prenatal Diagnosis in the Province of Cienfuegos between 2007 and 2010 |
| title_short | Cytogenetic Prenatal Diagnosis in the Province of Cienfuegos between 2007 and 2010 |
| title_sort | cytogenetic prenatal diagnosis in the province of cienfuegos between 2007 and 2010 |
| topic | diagnóstico prenatal análisis citogenético |
| url | http://medisur.sld.cu/index.php/medisur/article/view/1992 |
| work_keys_str_mv | AT pedroalidiazvelizjimenez cytogeneticprenataldiagnosisintheprovinceofcienfuegosbetween2007and2010 AT yamelisgarridomartinez cytogeneticprenataldiagnosisintheprovinceofcienfuegosbetween2007and2010 AT aimeguerrajorge cytogeneticprenataldiagnosisintheprovinceofcienfuegosbetween2007and2010 AT belkisvidalhernandez cytogeneticprenataldiagnosisintheprovinceofcienfuegosbetween2007and2010 |