Toxicity of silver nanoparticles on the clam Ruditapes decussatus assessed through biomarkers and clearance rate
The current bioassay aims the evaluation of the ecotoxicity of the silver nanoparticles (NPs) (100 and 200 μ g l ^−1 ) on Ruditapes decussatus after 48 h and 7 days of its exposure. The biochemical analyses performed at gills and digestive glands showed a disturbance of the antioxidant system follow...
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| Format: | Article |
| Language: | English |
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IOP Publishing
2021-01-01
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| Series: | Materials Research Express |
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| Online Access: | https://doi.org/10.1088/2053-1591/ac2c2f |
| _version_ | 1827869168004759552 |
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| author | Souhail Elyousfi Mohamed Dellali Ali Mezni Manel Ben Ali Amor Hedfi Mohammed Almalki Amine Mezni Melissa Rohal-Lupher Aida Dervishi Fehmi Boufahja |
| author_facet | Souhail Elyousfi Mohamed Dellali Ali Mezni Manel Ben Ali Amor Hedfi Mohammed Almalki Amine Mezni Melissa Rohal-Lupher Aida Dervishi Fehmi Boufahja |
| author_sort | Souhail Elyousfi |
| collection | DOAJ |
| description | The current bioassay aims the evaluation of the ecotoxicity of the silver nanoparticles (NPs) (100 and 200 μ g l ^−1 ) on Ruditapes decussatus after 48 h and 7 days of its exposure. The biochemical analyses performed at gills and digestive glands showed a disturbance of the antioxidant system following the exposure of clams to Ag NPs. The catalase activity was induced and varied significantly depending on the concentration of Ag NPs and the exposure time, as well as the organ analysed. Simultaneousely, a decrease in Gluthation S -Transferase activity was observed at all concentrations tested and organs considered. The acetylcholinesterase activity results confirmed that the threshold of Ag NPs able to disrupt the the cholinergic system was less than 100 μ g l ^−1 . In overall, silver nanoparticles had a significant caused antagonistic effect on clams in both oxidative- and cholinergic states. Furthermore the findings obtained in this study demonstrated that Ruditapes decussatus can employed as a potential bioindicative species in the assessment of the toxicity of such an emerging material as Ag NPs. |
| first_indexed | 2024-03-12T15:42:07Z |
| format | Article |
| id | doaj.art-638fb39ba1e3479c9617d980f0e5d7e2 |
| institution | Directory Open Access Journal |
| issn | 2053-1591 |
| language | English |
| last_indexed | 2024-03-12T15:42:07Z |
| publishDate | 2021-01-01 |
| publisher | IOP Publishing |
| record_format | Article |
| series | Materials Research Express |
| spelling | doaj.art-638fb39ba1e3479c9617d980f0e5d7e22023-08-09T15:56:15ZengIOP PublishingMaterials Research Express2053-15912021-01-0181010500510.1088/2053-1591/ac2c2fToxicity of silver nanoparticles on the clam Ruditapes decussatus assessed through biomarkers and clearance rateSouhail Elyousfi0Mohamed Dellali1Ali Mezni2Manel Ben Ali3Amor Hedfi4Mohammed Almalki5https://orcid.org/0000-0002-5407-4043Amine Mezni6https://orcid.org/0000-0002-2915-4834Melissa Rohal-Lupher7Aida Dervishi8Fehmi Boufahja9https://orcid.org/0000-0001-8220-0396University of Carthage , Faculty of Sciences of Bizerte, LR01ES14 Laboratory of Environment Biomonitoring, Coastal Ecology and Ecotoxicology Unit, 7021 Zarzouna, TunisiaUniversity of Carthage , Faculty of Sciences of Bizerte, LR01ES14 Laboratory of Environment Biomonitoring, Coastal Ecology and Ecotoxicology Unit, 7021 Zarzouna, TunisiaUniversity of Carthage , Faculty of Sciences of Bizerte, LR01ES14 Laboratory of Environment Biomonitoring, Coastal Ecology and Ecotoxicology Unit, 7021 Zarzouna, TunisiaDepartment of Biology, College of Sciences, Taif University , PO Box 11099, Taif 21944, Saudi ArabiaDepartment of Biology, College of Sciences, Taif University , PO Box 11099, Taif 21944, Saudi ArabiaDepartment of Biology, College of Sciences, Taif University , PO Box 11099, Taif 21944, Saudi ArabiaDepartment of Chemistry, College of Sciences, Taif University , PO Box 11099, Taif 21944, Saudi ArabiaTexas Water Development Board, 1700 North Congress Avenue, Austin, TX 78701, United States of AmericaDepartment of Biotechnology, Faculty of Natural Sciences, University of Tirana , Zog I, 25/1, 1001 Tirana, AlbaniaUniversity of Carthage , Faculty of Sciences of Bizerte, LR01ES14 Laboratory of Environment Biomonitoring, Coastal Ecology and Ecotoxicology Unit, 7021 Zarzouna, TunisiaThe current bioassay aims the evaluation of the ecotoxicity of the silver nanoparticles (NPs) (100 and 200 μ g l ^−1 ) on Ruditapes decussatus after 48 h and 7 days of its exposure. The biochemical analyses performed at gills and digestive glands showed a disturbance of the antioxidant system following the exposure of clams to Ag NPs. The catalase activity was induced and varied significantly depending on the concentration of Ag NPs and the exposure time, as well as the organ analysed. Simultaneousely, a decrease in Gluthation S -Transferase activity was observed at all concentrations tested and organs considered. The acetylcholinesterase activity results confirmed that the threshold of Ag NPs able to disrupt the the cholinergic system was less than 100 μ g l ^−1 . In overall, silver nanoparticles had a significant caused antagonistic effect on clams in both oxidative- and cholinergic states. Furthermore the findings obtained in this study demonstrated that Ruditapes decussatus can employed as a potential bioindicative species in the assessment of the toxicity of such an emerging material as Ag NPs.https://doi.org/10.1088/2053-1591/ac2c2fsilver nanoparticlesruditapes decussatusbiomarkersoxidative stressclearance rate |
| spellingShingle | Souhail Elyousfi Mohamed Dellali Ali Mezni Manel Ben Ali Amor Hedfi Mohammed Almalki Amine Mezni Melissa Rohal-Lupher Aida Dervishi Fehmi Boufahja Toxicity of silver nanoparticles on the clam Ruditapes decussatus assessed through biomarkers and clearance rate Materials Research Express silver nanoparticles ruditapes decussatus biomarkers oxidative stress clearance rate |
| title | Toxicity of silver nanoparticles on the clam Ruditapes decussatus assessed through biomarkers and clearance rate |
| title_full | Toxicity of silver nanoparticles on the clam Ruditapes decussatus assessed through biomarkers and clearance rate |
| title_fullStr | Toxicity of silver nanoparticles on the clam Ruditapes decussatus assessed through biomarkers and clearance rate |
| title_full_unstemmed | Toxicity of silver nanoparticles on the clam Ruditapes decussatus assessed through biomarkers and clearance rate |
| title_short | Toxicity of silver nanoparticles on the clam Ruditapes decussatus assessed through biomarkers and clearance rate |
| title_sort | toxicity of silver nanoparticles on the clam ruditapes decussatus assessed through biomarkers and clearance rate |
| topic | silver nanoparticles ruditapes decussatus biomarkers oxidative stress clearance rate |
| url | https://doi.org/10.1088/2053-1591/ac2c2f |
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