Corticosteroid Treatment for Central Nervous System Infections

Infectious diseases of the central nervous system (CNS) cause inflammatory processes within the brain and spinal cord that can lead to morbidity and mortality in a high proportion of patients. Pharmacological strategies to dampen inflammation have been investigated, and steroids are one of the adjun...

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Main Author: Dong Hoon Shin
Format: Article
Language:English
Published: The Korean Neurocritical Care Society 2017-12-01
Series:Journal of Neurocritical Care
Subjects:
Online Access:http://www.e-jnc.org/upload/pdf/jnc-170024.pdf
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author Dong Hoon Shin
author_facet Dong Hoon Shin
author_sort Dong Hoon Shin
collection DOAJ
description Infectious diseases of the central nervous system (CNS) cause inflammatory processes within the brain and spinal cord that can lead to morbidity and mortality in a high proportion of patients. Pharmacological strategies to dampen inflammation have been investigated, and steroids are one of the adjunctive treatments for bacterial meningitis, tuberculous meningitis, and herpes simplex virus encephalitis. In this paper, we review the recent literature that provides guidelines for the use of steroids in combination with appropriate antimicrobial therapy, and we discuss how systemic steroid treatment is an important aspect of treatment regimens for CNS infectious diseases.
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spelling doaj.art-6390cddc748b4ee2ac61fdfc52e33f6b2022-12-21T18:48:12ZengThe Korean Neurocritical Care SocietyJournal of Neurocritical Care2005-03482508-13492017-12-01102697510.18700/jnc.170024270Corticosteroid Treatment for Central Nervous System InfectionsDong Hoon Shin0Department of Neurology, Gachon University Gil Medical Center, Incheon, KoreaInfectious diseases of the central nervous system (CNS) cause inflammatory processes within the brain and spinal cord that can lead to morbidity and mortality in a high proportion of patients. Pharmacological strategies to dampen inflammation have been investigated, and steroids are one of the adjunctive treatments for bacterial meningitis, tuberculous meningitis, and herpes simplex virus encephalitis. In this paper, we review the recent literature that provides guidelines for the use of steroids in combination with appropriate antimicrobial therapy, and we discuss how systemic steroid treatment is an important aspect of treatment regimens for CNS infectious diseases.http://www.e-jnc.org/upload/pdf/jnc-170024.pdfSteroidsMeningitis, BacterialTuberculosisEncephalitis
spellingShingle Dong Hoon Shin
Corticosteroid Treatment for Central Nervous System Infections
Journal of Neurocritical Care
Steroids
Meningitis, Bacterial
Tuberculosis
Encephalitis
title Corticosteroid Treatment for Central Nervous System Infections
title_full Corticosteroid Treatment for Central Nervous System Infections
title_fullStr Corticosteroid Treatment for Central Nervous System Infections
title_full_unstemmed Corticosteroid Treatment for Central Nervous System Infections
title_short Corticosteroid Treatment for Central Nervous System Infections
title_sort corticosteroid treatment for central nervous system infections
topic Steroids
Meningitis, Bacterial
Tuberculosis
Encephalitis
url http://www.e-jnc.org/upload/pdf/jnc-170024.pdf
work_keys_str_mv AT donghoonshin corticosteroidtreatmentforcentralnervoussysteminfections