LM-GVP: an extensible sequence and structure informed deep learning framework for protein property prediction

Abstract Proteins perform many essential functions in biological systems and can be successfully developed as bio-therapeutics. It is invaluable to be able to predict their properties based on a proposed sequence and structure. In this study, we developed a novel generalizable deep learning framewor...

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Bibliographic Details
Main Authors: Zichen Wang, Steven A. Combs, Ryan Brand, Miguel Romero Calvo, Panpan Xu, George Price, Nataliya Golovach, Emmanuel O. Salawu, Colby J. Wise, Sri Priya Ponnapalli, Peter M. Clark
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-10775-y