Unique and shared inflammatory profiles of human brain endothelia and pericytes

Unique and shared inflammatory profiles of human brain endothelia and pericytes

Abstract Background Pericytes and endothelial cells are critical cellular components of the blood-brain barrier (BBB) and play an important role in neuroinflammation. To date, the majority of inflammation-related studies in endothelia and pericytes have been carried out using immortalised cell lines...

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Bibliographic Details
Main Authors: Leon C. D. Smyth, Justin Rustenhoven, Thomas I.-H. Park, Patrick Schweder, Deidre Jansson, Peter A. Heppner, Simon J. O’Carroll, Edward W. Mee, Richard L. M. Faull, Maurice Curtis, Mike Dragunow
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Journal of Neuroinflammation
Subjects:
Neurovascular
Blood-brain barrier
Neuroinflammation
IL-1β
SMAD2/3
IGFBP
Online Access:http://link.springer.com/article/10.1186/s12974-018-1167-8

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