Growth in a biofilm promotes conjugation of a blaNDM-1-bearing plasmid between Klebsiella pneumoniae strains

Growth in a biofilm promotes conjugation of a blaNDM-1-bearing plasmid between Klebsiella pneumoniae strains

ABSTRACT Antimicrobial resistance (AMR) is a growing problem, especially in Gram-negative Enterobacteriaceae such as Klebsiella pneumoniae. Horizontal transfer of conjugative plasmids contributes to AMR gene dissemination. Bacteria such as K. pneumoniae commonly exist in biofilms, yet most studies f...

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Bibliographic Details
Main Authors: Sarah J. Element, Robert A. Moran, Emilie Beattie, Rebecca J. Hall, Willem van Schaik, Michelle M.C. Buckner
Format: Article
Language:English
Published: American Society for Microbiology 2023-08-01
Series:mSphere
Subjects:
carbapenemase
carbapenem-resistance plasmid
Klebsiella pneumoniae
conjugation
biofilm
gene expression
Online Access:https://journals.asm.org/doi/10.1128/msphere.00170-23

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