Evaluation of the neurotoxic effects of intrathecal administration of (S)-(+)-Ketoprofen on rat spinal cords: randomized controlled experimental study

Evaluation of the neurotoxic effects of intrathecal administration of (S)-(+)-Ketoprofen on rat spinal cords: randomized controlled experimental study

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Abstract Background and objectives Intrathecal administration of non-steroidal anti-inflammatory drugs is more efficacious for post-operative pain management. Cyclooxygenase inhibiting non-steroidal anti-inflammatory drugs like (S)-(+)-Ketoprofen, may be effective at lower intrathecal doses than pa...

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Bibliographic Details
Main Authors: Cengiz Kaya, Yunus O. Atalay, Bilge C. Meydan, Yasemin B. Ustun, Ersin Koksal, Sultan Caliskan
Format: Article
Language:English
Published: Sociedade Brasileira de Anestesiologia 2019-10-01
Series:Revista Brasileira de Anestesiologia
Subjects:
Cyclooxygenase inhibitor
Intrathecal injection
(S)-(+)-Ketoprofen
Neurotoxicity
Inflammation
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-70942019000400011&tlng=pt

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