Diffuse plane xanthomatosis associated with monoclonal gammopathy Xantomatose plana difusa associada a gamopatia monoclonal
Diffuse plane normolipemic xanthomatosis (DPNX) is a rare, non-inherited disease that is often associated with systemic diseases, mainly malignant hematological (especially multiple myeloma) or lymph proliferative disorders. The DPNX can precede the appearance of such conditions by several years, so...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Dermatologia
2011-08-01
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| Series: | Anais Brasileiros de Dermatologia |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962011000700012 |
| _version_ | 1818143035910782976 |
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| author | Aristóteles Rosmaninho Iolanda Fernandes Arlindo Guimas Isabel Amorim Manuela Selores |
| author_facet | Aristóteles Rosmaninho Iolanda Fernandes Arlindo Guimas Isabel Amorim Manuela Selores |
| author_sort | Aristóteles Rosmaninho |
| collection | DOAJ |
| description | Diffuse plane normolipemic xanthomatosis (DPNX) is a rare, non-inherited disease that is often associated with systemic diseases, mainly malignant hematological (especially multiple myeloma) or lymph proliferative disorders. The DPNX can precede the appearance of such conditions by several years, so careful follow-up and periodic laboratory examinations are recommended even for patients that seemed to have no underlying disease. We describe a case associated with monoclonal gammopathy. This case shows that dermatological lesions can be the first manifestation of important hematological diseases and so physicians should be familiarized with this entity<br>A xantomatose plana difusa normolipêmica (XPDN) é uma dermatose adquirida rara, muitas vezes associada a doenças sistêmicas, nomeadamente neoplasias hematológicas(sobretudo o mieloma múltiplo) ou a processos linfoproliferativos. A XPDN pode preceder o aparecimento dessas doenças em vários anos, sendo por isso recomendada uma vigilância clínica e laboratorial periódica, mesmo para os doentes que aparentemente não apresentam uma doença associada. Descrevemos um caso associado à gamopatia monoclonal. Este caso demonstra a importância das manifestações cutâneas como primeira manifestação de doenças hematológicas importantes e por isso os clínicos devem estar familiarizados com esta entidade |
| first_indexed | 2024-12-11T11:25:16Z |
| format | Article |
| id | doaj.art-6399a5fba2dd4f349c83199b7a798ee0 |
| institution | Directory Open Access Journal |
| issn | 0365-0596 1806-4841 |
| language | English |
| last_indexed | 2024-12-11T11:25:16Z |
| publishDate | 2011-08-01 |
| publisher | Sociedade Brasileira de Dermatologia |
| record_format | Article |
| series | Anais Brasileiros de Dermatologia |
| spelling | doaj.art-6399a5fba2dd4f349c83199b7a798ee02022-12-22T01:09:02ZengSociedade Brasileira de DermatologiaAnais Brasileiros de Dermatologia0365-05961806-48412011-08-01864505210.1590/S0365-05962011000700012Diffuse plane xanthomatosis associated with monoclonal gammopathy Xantomatose plana difusa associada a gamopatia monoclonalAristóteles RosmaninhoIolanda FernandesArlindo GuimasIsabel AmorimManuela SeloresDiffuse plane normolipemic xanthomatosis (DPNX) is a rare, non-inherited disease that is often associated with systemic diseases, mainly malignant hematological (especially multiple myeloma) or lymph proliferative disorders. The DPNX can precede the appearance of such conditions by several years, so careful follow-up and periodic laboratory examinations are recommended even for patients that seemed to have no underlying disease. We describe a case associated with monoclonal gammopathy. This case shows that dermatological lesions can be the first manifestation of important hematological diseases and so physicians should be familiarized with this entity<br>A xantomatose plana difusa normolipêmica (XPDN) é uma dermatose adquirida rara, muitas vezes associada a doenças sistêmicas, nomeadamente neoplasias hematológicas(sobretudo o mieloma múltiplo) ou a processos linfoproliferativos. A XPDN pode preceder o aparecimento dessas doenças em vários anos, sendo por isso recomendada uma vigilância clínica e laboratorial periódica, mesmo para os doentes que aparentemente não apresentam uma doença associada. Descrevemos um caso associado à gamopatia monoclonal. Este caso demonstra a importância das manifestações cutâneas como primeira manifestação de doenças hematológicas importantes e por isso os clínicos devem estar familiarizados com esta entidadehttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962011000700012Mieloma múltiploParaproteinemiasXantomatosemultiple MyelomaParaproteinemiasXanthomatosis |
| spellingShingle | Aristóteles Rosmaninho Iolanda Fernandes Arlindo Guimas Isabel Amorim Manuela Selores Diffuse plane xanthomatosis associated with monoclonal gammopathy Xantomatose plana difusa associada a gamopatia monoclonal Anais Brasileiros de Dermatologia Mieloma múltiplo Paraproteinemias Xantomatose multiple Myeloma Paraproteinemias Xanthomatosis |
| title | Diffuse plane xanthomatosis associated with monoclonal gammopathy Xantomatose plana difusa associada a gamopatia monoclonal |
| title_full | Diffuse plane xanthomatosis associated with monoclonal gammopathy Xantomatose plana difusa associada a gamopatia monoclonal |
| title_fullStr | Diffuse plane xanthomatosis associated with monoclonal gammopathy Xantomatose plana difusa associada a gamopatia monoclonal |
| title_full_unstemmed | Diffuse plane xanthomatosis associated with monoclonal gammopathy Xantomatose plana difusa associada a gamopatia monoclonal |
| title_short | Diffuse plane xanthomatosis associated with monoclonal gammopathy Xantomatose plana difusa associada a gamopatia monoclonal |
| title_sort | diffuse plane xanthomatosis associated with monoclonal gammopathy xantomatose plana difusa associada a gamopatia monoclonal |
| topic | Mieloma múltiplo Paraproteinemias Xantomatose multiple Myeloma Paraproteinemias Xanthomatosis |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962011000700012 |
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