Berberine suppresses the ectopic expression of miR-133a in endothelial cells to improve vascular dementia in diabetic rats

Berberine suppresses the ectopic expression of miR-133a in endothelial cells to improve vascular dementia in diabetic rats

Objective: Vascular dementia is the second leading cause of dementia, which is strongly associated with diabetes. Ectopic expression of miR-133a in endothelial cells is involved in endothelial dysfunction in diabetes. Whether berberine, as a natural product in Coptis chinensis, improves vascular dem...

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Bibliographic Details
Main Authors: Sen Yin, Wenwu Bai, Peng Li, Xu Jian, Tichao Shan, Zhenyu Tang, Xuejiao Jing, Song Ping, Quanzhong Li, Zhang Miao, Shuangxi Wang, Wensheng Ou, Jianchun Fei, Tao Guo
Format: Article
Language:English
Published: Taylor & Francis Group 2019-11-01
Series:Clinical and Experimental Hypertension
Subjects:
berberine
vascular dementia
diabetes
mir-133a
gtpch1
Online Access:http://dx.doi.org/10.1080/10641963.2018.1545846

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