Frequently asked questions about the ISAPP postbiotic definition

The term postbiotic was defined by the International Scientific Association of Probiotics and Prebiotics (ISAPP) as “a preparation of inanimate microorganisms and/or their components that confers a health benefit on the host.” Although the ISAPP definition is widely cited, some concerns were aired a...

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Main Authors: Gabriel Vinderola, Mary Ellen Sanders, Marla Cunningham, Colin Hill
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1324565/full
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author Gabriel Vinderola
Mary Ellen Sanders
Marla Cunningham
Colin Hill
author_facet Gabriel Vinderola
Mary Ellen Sanders
Marla Cunningham
Colin Hill
author_sort Gabriel Vinderola
collection DOAJ
description The term postbiotic was defined by the International Scientific Association of Probiotics and Prebiotics (ISAPP) as “a preparation of inanimate microorganisms and/or their components that confers a health benefit on the host.” Although the ISAPP definition is widely cited, some concerns were aired after publication, and alternative definitions of postbiotic, as well as different terms for inactivated microbes, have been previously suggested. This paper addresses questions about the ISAPP definition that have been raised in different forums, including scientific meetings, social media commentary and personal communications. We focus on the rationale, scope, wording, composition and commercial implementation, as well as what is expected of postbiotics regarding safety, efficacy, quantification and mechanisms of action. We hope that exploring these questions will further clarify the definition and its scope and support a common understanding of the concept of postbiotics.
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spelling doaj.art-63a3b59121de40c39aa03c06285a82672024-01-10T11:56:09ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2024-01-011410.3389/fmicb.2023.13245651324565Frequently asked questions about the ISAPP postbiotic definitionGabriel Vinderola0Mary Ellen Sanders1Marla Cunningham2Colin Hill3Instituto de Lactología Industrial (CONICET-UNL), Faculty of Chemical Engineering, National University of Litoral, Santa Fe, ArgentinaInternational Scientific Association for Probiotics and Prebiotics, Centennial, CO, United StatesInternational Scientific Association for Probiotics and Prebiotics, Brisbane, QLD, AustraliaAPC Microbiome Ireland, University College Cork, Cork, IrelandThe term postbiotic was defined by the International Scientific Association of Probiotics and Prebiotics (ISAPP) as “a preparation of inanimate microorganisms and/or their components that confers a health benefit on the host.” Although the ISAPP definition is widely cited, some concerns were aired after publication, and alternative definitions of postbiotic, as well as different terms for inactivated microbes, have been previously suggested. This paper addresses questions about the ISAPP definition that have been raised in different forums, including scientific meetings, social media commentary and personal communications. We focus on the rationale, scope, wording, composition and commercial implementation, as well as what is expected of postbiotics regarding safety, efficacy, quantification and mechanisms of action. We hope that exploring these questions will further clarify the definition and its scope and support a common understanding of the concept of postbiotics.https://www.frontiersin.org/articles/10.3389/fmicb.2023.1324565/fullpostbioticsInternational Scientific Association for Probiotics and PrebioticsISAPPbioticinanimate microorganism
spellingShingle Gabriel Vinderola
Mary Ellen Sanders
Marla Cunningham
Colin Hill
Frequently asked questions about the ISAPP postbiotic definition
Frontiers in Microbiology
postbiotics
International Scientific Association for Probiotics and Prebiotics
ISAPP
biotic
inanimate microorganism
title Frequently asked questions about the ISAPP postbiotic definition
title_full Frequently asked questions about the ISAPP postbiotic definition
title_fullStr Frequently asked questions about the ISAPP postbiotic definition
title_full_unstemmed Frequently asked questions about the ISAPP postbiotic definition
title_short Frequently asked questions about the ISAPP postbiotic definition
title_sort frequently asked questions about the isapp postbiotic definition
topic postbiotics
International Scientific Association for Probiotics and Prebiotics
ISAPP
biotic
inanimate microorganism
url https://www.frontiersin.org/articles/10.3389/fmicb.2023.1324565/full
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