Developmental transcriptomic patterns can be altered by transgenic overexpression of Uty

Abstract The genetic material encoded on X and Y chromosomes provides the foundation by which biological sex differences are established. Epigenetic regulators expressed on these sex chromosomes, including Kdm6a (Utx), Kdm5c, and Ddx3x have far-reaching impacts on transcriptional control of phenotyp...

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Bibliographic Details
Main Authors: Kylie D. Rock, Lillian M. Folts, Hannah C. Zierden, Ruth Marx-Rattner, Nicolae Adrian Leu, Bridget M. Nugent, Tracy L. Bale
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-47977-x