Current Practice of High Flow through Nasal Cannula in Exacerbated COPD Patients
Acute Exacerbation of Chronic Obstructive Pulmonary Disease is a form of severe Acute Respiratory Failure (ARF) requiring Conventional Oxygen Therapy (COT) in the case of absence of acidosis or the application of Non-Invasive Ventilation (NIV) in case of respiratory acidosis. In the last decade, Hig...
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-03-01
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| Series: | Healthcare |
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| Online Access: | https://www.mdpi.com/2227-9032/10/3/536 |
| _version_ | 1797471240044150784 |
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| author | Andrea Bruni Eugenio Garofalo Daniela Procopio Silvia Corrado Antonio Caroleo Eugenio Biamonte Corrado Pelaia Federico Longhini |
| author_facet | Andrea Bruni Eugenio Garofalo Daniela Procopio Silvia Corrado Antonio Caroleo Eugenio Biamonte Corrado Pelaia Federico Longhini |
| author_sort | Andrea Bruni |
| collection | DOAJ |
| description | Acute Exacerbation of Chronic Obstructive Pulmonary Disease is a form of severe Acute Respiratory Failure (ARF) requiring Conventional Oxygen Therapy (COT) in the case of absence of acidosis or the application of Non-Invasive Ventilation (NIV) in case of respiratory acidosis. In the last decade, High Flow through Nasal Cannula (HFNC) has been increasingly used, mainly in patients with hypoxemic ARF. However, some studies were also published in AECOPD patients, and some evidence emerged. In this review, after describing the mechanism underlying potential clinical benefits, we analyzed the possible clinical application of HFNC to AECOPD patients. In the case of respiratory acidosis, the gold-standard treatment remains NIV, supported by strong evidence in favor. However, HFNC may be considered as an alternative to NIV if the latter fails for intolerance. HFNC should also be considered and preferred to COT at NIV breaks and weaning. Finally, HFNC should also be preferred to COT as first-line oxygen treatment in AECOPD patients without respiratory acidosis. |
| first_indexed | 2024-03-09T19:46:20Z |
| format | Article |
| id | doaj.art-63a99102a0c04191bad1216212bd96b6 |
| institution | Directory Open Access Journal |
| issn | 2227-9032 |
| language | English |
| last_indexed | 2024-03-09T19:46:20Z |
| publishDate | 2022-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Healthcare |
| spelling | doaj.art-63a99102a0c04191bad1216212bd96b62023-11-24T01:23:06ZengMDPI AGHealthcare2227-90322022-03-0110353610.3390/healthcare10030536Current Practice of High Flow through Nasal Cannula in Exacerbated COPD PatientsAndrea Bruni0Eugenio Garofalo1Daniela Procopio2Silvia Corrado3Antonio Caroleo4Eugenio Biamonte5Corrado Pelaia6Federico Longhini7Anesthesia and Intensive Care Unit, Department of Medical and Surgical Sciences, University Hospital Mater Domini, Magna Graecia University, 88100 Catanzaro, ItalyAnesthesia and Intensive Care Unit, Department of Medical and Surgical Sciences, University Hospital Mater Domini, Magna Graecia University, 88100 Catanzaro, ItalyAnesthesia and Intensive Care Unit, Department of Medical and Surgical Sciences, University Hospital Mater Domini, Magna Graecia University, 88100 Catanzaro, ItalyAnesthesia and Intensive Care Unit, Department of Medical and Surgical Sciences, University Hospital Mater Domini, Magna Graecia University, 88100 Catanzaro, ItalyAnesthesia and Intensive Care Unit, Department of Medical and Surgical Sciences, University Hospital Mater Domini, Magna Graecia University, 88100 Catanzaro, ItalyAnesthesia and Intensive Care Unit, Department of Medical and Surgical Sciences, University Hospital Mater Domini, Magna Graecia University, 88100 Catanzaro, ItalyAnesthesia and Intensive Care Unit, Department of Medical and Surgical Sciences, University Hospital Mater Domini, Magna Graecia University, 88100 Catanzaro, ItalyAnesthesia and Intensive Care Unit, Department of Medical and Surgical Sciences, University Hospital Mater Domini, Magna Graecia University, 88100 Catanzaro, ItalyAcute Exacerbation of Chronic Obstructive Pulmonary Disease is a form of severe Acute Respiratory Failure (ARF) requiring Conventional Oxygen Therapy (COT) in the case of absence of acidosis or the application of Non-Invasive Ventilation (NIV) in case of respiratory acidosis. In the last decade, High Flow through Nasal Cannula (HFNC) has been increasingly used, mainly in patients with hypoxemic ARF. However, some studies were also published in AECOPD patients, and some evidence emerged. In this review, after describing the mechanism underlying potential clinical benefits, we analyzed the possible clinical application of HFNC to AECOPD patients. In the case of respiratory acidosis, the gold-standard treatment remains NIV, supported by strong evidence in favor. However, HFNC may be considered as an alternative to NIV if the latter fails for intolerance. HFNC should also be considered and preferred to COT at NIV breaks and weaning. Finally, HFNC should also be preferred to COT as first-line oxygen treatment in AECOPD patients without respiratory acidosis.https://www.mdpi.com/2227-9032/10/3/536Chronic Obstructive Pulmonary Diseaseoxygenhigh flow nasal cannulanon-invasive ventilationrespiratory therapyrespiratory insufficiency |
| spellingShingle | Andrea Bruni Eugenio Garofalo Daniela Procopio Silvia Corrado Antonio Caroleo Eugenio Biamonte Corrado Pelaia Federico Longhini Current Practice of High Flow through Nasal Cannula in Exacerbated COPD Patients Healthcare Chronic Obstructive Pulmonary Disease oxygen high flow nasal cannula non-invasive ventilation respiratory therapy respiratory insufficiency |
| title | Current Practice of High Flow through Nasal Cannula in Exacerbated COPD Patients |
| title_full | Current Practice of High Flow through Nasal Cannula in Exacerbated COPD Patients |
| title_fullStr | Current Practice of High Flow through Nasal Cannula in Exacerbated COPD Patients |
| title_full_unstemmed | Current Practice of High Flow through Nasal Cannula in Exacerbated COPD Patients |
| title_short | Current Practice of High Flow through Nasal Cannula in Exacerbated COPD Patients |
| title_sort | current practice of high flow through nasal cannula in exacerbated copd patients |
| topic | Chronic Obstructive Pulmonary Disease oxygen high flow nasal cannula non-invasive ventilation respiratory therapy respiratory insufficiency |
| url | https://www.mdpi.com/2227-9032/10/3/536 |
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