SARS-CoV-2 antibody determination in a vaccinated and recovered cohort in Austria

Since December 2019 the world has been dealing with a severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) pandemic. The first SARS-CoV-2 vaccine was made available in Europe at the end of 2020. 202 volunteers from the vicinity of the University of Applied Sciences Wiener Neustadt took...

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Main Authors: Elisabeth Mara, Tobias Mader, Johannes Gratzer, Stefanie Hochegger, Thomas Pekar
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Clinical Immunology Communications
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2772613422000178
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author Elisabeth Mara
Tobias Mader
Johannes Gratzer
Stefanie Hochegger
Thomas Pekar
author_facet Elisabeth Mara
Tobias Mader
Johannes Gratzer
Stefanie Hochegger
Thomas Pekar
author_sort Elisabeth Mara
collection DOAJ
description Since December 2019 the world has been dealing with a severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) pandemic. The first SARS-CoV-2 vaccine was made available in Europe at the end of 2020. 202 volunteers from the vicinity of the University of Applied Sciences Wiener Neustadt took part in this study; their IgG levels recognizing the RBD of SARS-CoV-2 were determined. The aim was to evaluate the SARS-CoV-2 titer levels of vaccinated, recovered and vaccinated plus recovered persons. We could show that there is a significant difference in the antibody levels of vaccinated, vaccinated plus recovered and only recovered probands. Additionally, the highest antibody levels were found in triple vaccinated persons. Furthermore, the Moderna vaccine seems to have a higher immune response.
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spelling doaj.art-63ab339e91fe42f1b5bdfd04252d55d12022-12-22T04:32:32ZengElsevierClinical Immunology Communications2772-61342022-12-012136141SARS-CoV-2 antibody determination in a vaccinated and recovered cohort in AustriaElisabeth Mara0Tobias Mader1Johannes Gratzer2Stefanie Hochegger3Thomas Pekar4Corresponding author.; Biomedical Science, University of Applied Sciences Wiener Neustadt, AustriaBiomedical Science, University of Applied Sciences Wiener Neustadt, AustriaBiomedical Science, University of Applied Sciences Wiener Neustadt, AustriaBiomedical Science, University of Applied Sciences Wiener Neustadt, AustriaBiomedical Science, University of Applied Sciences Wiener Neustadt, AustriaSince December 2019 the world has been dealing with a severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) pandemic. The first SARS-CoV-2 vaccine was made available in Europe at the end of 2020. 202 volunteers from the vicinity of the University of Applied Sciences Wiener Neustadt took part in this study; their IgG levels recognizing the RBD of SARS-CoV-2 were determined. The aim was to evaluate the SARS-CoV-2 titer levels of vaccinated, recovered and vaccinated plus recovered persons. We could show that there is a significant difference in the antibody levels of vaccinated, vaccinated plus recovered and only recovered probands. Additionally, the highest antibody levels were found in triple vaccinated persons. Furthermore, the Moderna vaccine seems to have a higher immune response.http://www.sciencedirect.com/science/article/pii/S2772613422000178SARS-CoV-2RBDIgG determinationVaccine
spellingShingle Elisabeth Mara
Tobias Mader
Johannes Gratzer
Stefanie Hochegger
Thomas Pekar
SARS-CoV-2 antibody determination in a vaccinated and recovered cohort in Austria
Clinical Immunology Communications
SARS-CoV-2
RBD
IgG determination
Vaccine
title SARS-CoV-2 antibody determination in a vaccinated and recovered cohort in Austria
title_full SARS-CoV-2 antibody determination in a vaccinated and recovered cohort in Austria
title_fullStr SARS-CoV-2 antibody determination in a vaccinated and recovered cohort in Austria
title_full_unstemmed SARS-CoV-2 antibody determination in a vaccinated and recovered cohort in Austria
title_short SARS-CoV-2 antibody determination in a vaccinated and recovered cohort in Austria
title_sort sars cov 2 antibody determination in a vaccinated and recovered cohort in austria
topic SARS-CoV-2
RBD
IgG determination
Vaccine
url http://www.sciencedirect.com/science/article/pii/S2772613422000178
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