Identification of genes involved in Ca<sup>2+ </sup>ionophore A23187-mediated apoptosis and demonstration of a high susceptibility for transcriptional repression of cell cycle genes in B lymphoblasts from a patient with Scott syndrome

Identification of genes involved in Ca<sup>2+ </sup>ionophore A23187-mediated apoptosis and demonstration of a high susceptibility for transcriptional repression of cell cycle genes in B lymphoblasts from a patient with Scott syndrome

<p>Abstract</p> <p>Background</p> <p>In contrast to other agents able to induce apoptosis of cultured cells, Ca<sup>2+ </sup>ionophore A23187 was shown to elicit direct activation of intracellular signal(s). The phenotype of the cells derived from patients h...

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Main Authors: Meyer Dominique, Schumann Beatrice, Martinez Marie-Carmen, Galitzine Marie, Nitsche Almut, Proulle Valérie, Kozian Detlef, Herrmann Matthias, Freyssinet Jean-Marie, Kerbiriou-Nabias Danièle
Format: Article
Language:English
Published: BMC 2005-10-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/6/146

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