Behçet's disease with multiple splenic abscesses in a child

We report the case of a 5-year-old male patient with multiple aseptic splenic abscesses associated with Behçet's disease. The patient visited Gachon University Gil Hospital with fever, abdominal pain, and acute watery and bloody diarrhea, and reported a 2-year history of chronic abdominal pain...

Full description

Bibliographic Details
Main Authors: Kyung In Lim, Dong Hwa Yang, Eell Ryoo
Format: Article
Language:English
Published: Korean Association for the Study of Intestinal Diseases 2017-07-01
Series:Intestinal Research
Subjects:
Online Access:https://doi.org/10.5217/ir.2017.15.3.422
_version_ 1818501882480427008
author Kyung In Lim
Dong Hwa Yang
Eell Ryoo
author_facet Kyung In Lim
Dong Hwa Yang
Eell Ryoo
author_sort Kyung In Lim
collection DOAJ
description We report the case of a 5-year-old male patient with multiple aseptic splenic abscesses associated with Behçet's disease. The patient visited Gachon University Gil Hospital with fever, abdominal pain, and acute watery and bloody diarrhea, and reported a 2-year history of chronic abdominal pain and intermittent watery diarrhea. He was treated with antibiotics at a local clinic for fever and cervical lymph node swelling. Additionally, he had recurrent stomatitis. A colonoscopy showed multiple well-demarcated ulcerations throughout the colon, and abdominal computed tomography showed multiple splenic abscesses. Pathergy and HLA-B51 tests were positive. Investigations did not reveal any infectious organisms in the aspirate obtained via ultrasound-guided fine needle aspiration. After steroid treatment, all symptoms and multiple aseptic splenic abscesses resolved. However, oral ulcers, genital ulcers, and abdominal pain recurred after tapering the steroids. Infliximab treatment improved the patient's symptoms. However, 5 months after the treatment, the symptoms recurred. The treatment was changed to include adalimumab. Subsequently, the patient's symptoms resolved and colonoscopic findings improved. No recurrence was noted after 3 months of follow-up.
first_indexed 2024-12-10T21:02:24Z
format Article
id doaj.art-63abb2ae322d468bab025700bab85706
institution Directory Open Access Journal
issn 1598-9100
language English
last_indexed 2024-12-10T21:02:24Z
publishDate 2017-07-01
publisher Korean Association for the Study of Intestinal Diseases
record_format Article
series Intestinal Research
spelling doaj.art-63abb2ae322d468bab025700bab857062022-12-22T01:33:45ZengKorean Association for the Study of Intestinal DiseasesIntestinal Research1598-91002017-07-0115342242810.5217/ir.2017.15.3.422ir.2017.15.3.422Behçet's disease with multiple splenic abscesses in a childKyung In Lim0Dong Hwa Yang1Eell Ryoo2Department of Pediatrics, Gachon University Gil Hospital, Incheon, Korea.Department of Pediatrics, Gachon University Gil Hospital, Incheon, Korea.Department of Pediatrics, Gachon University Gil Hospital, Incheon, Korea.We report the case of a 5-year-old male patient with multiple aseptic splenic abscesses associated with Behçet's disease. The patient visited Gachon University Gil Hospital with fever, abdominal pain, and acute watery and bloody diarrhea, and reported a 2-year history of chronic abdominal pain and intermittent watery diarrhea. He was treated with antibiotics at a local clinic for fever and cervical lymph node swelling. Additionally, he had recurrent stomatitis. A colonoscopy showed multiple well-demarcated ulcerations throughout the colon, and abdominal computed tomography showed multiple splenic abscesses. Pathergy and HLA-B51 tests were positive. Investigations did not reveal any infectious organisms in the aspirate obtained via ultrasound-guided fine needle aspiration. After steroid treatment, all symptoms and multiple aseptic splenic abscesses resolved. However, oral ulcers, genital ulcers, and abdominal pain recurred after tapering the steroids. Infliximab treatment improved the patient's symptoms. However, 5 months after the treatment, the symptoms recurred. The treatment was changed to include adalimumab. Subsequently, the patient's symptoms resolved and colonoscopic findings improved. No recurrence was noted after 3 months of follow-up.https://doi.org/10.5217/ir.2017.15.3.422Behcet syndromeSpleenAbscessPediatrics
spellingShingle Kyung In Lim
Dong Hwa Yang
Eell Ryoo
Behçet's disease with multiple splenic abscesses in a child
Intestinal Research
Behcet syndrome
Spleen
Abscess
Pediatrics
title Behçet's disease with multiple splenic abscesses in a child
title_full Behçet's disease with multiple splenic abscesses in a child
title_fullStr Behçet's disease with multiple splenic abscesses in a child
title_full_unstemmed Behçet's disease with multiple splenic abscesses in a child
title_short Behçet's disease with multiple splenic abscesses in a child
title_sort behcet s disease with multiple splenic abscesses in a child
topic Behcet syndrome
Spleen
Abscess
Pediatrics
url https://doi.org/10.5217/ir.2017.15.3.422
work_keys_str_mv AT kyunginlim behcetsdiseasewithmultiplesplenicabscessesinachild
AT donghwayang behcetsdiseasewithmultiplesplenicabscessesinachild
AT eellryoo behcetsdiseasewithmultiplesplenicabscessesinachild