Vasoactive intestinal peptide exerts therapeutic action by regulating PTEN in a model of Sjögren's disease

Vasoactive intestinal peptide exerts therapeutic action by regulating PTEN in a model of Sjögren's disease

Abstract Introduction Sjögren's disease (SjD) is a chronic autoimmune disease characterized by the loss of the secretory function of the exocrine glands. At present, drugs that can both correct the immune imbalance and improve exocrine gland function are needed. Meanwhile, vasoactive intestinal...

Full description

Bibliographic Details
Main Authors:	Yixi Li, Wen Zhu, Rui Lin, Junjie Zhao, Yue Wang
Format:	Article
Language:	English
Published:	Wiley 2023-07-01
Series:	Immunity, Inflammation and Disease
Subjects:	PI3K/AKT PTEN Sjögren's disease Treg/Th17 vasoactive intestinal peptide
Online Access:	https://doi.org/10.1002/iid3.936

Similar Items

Vasoactive intestinal polypeptide level in gastroesophageal reflux disease before and after surgical treatment
by: Ye. I. Haidarzhi, et al.
Published: (2023-07-01)

Immunomodulatory role of vasoactive intestinal peptide and ghrelin in Oncorhynchus mykiss
by: Carolina Muñoz-Flores, et al.
Published: (2023-12-01)

Effect of Acrylamide Supplementation on the Population of Vasoactive Intestinal Peptide (VIP)-Like Immunoreactive Neurons in the Porcine Small Intestine
by: Katarzyna Palus, et al.
Published: (2020-12-01)

Pressure-Dependent Elevation of Vasoactive Intestinal Peptide Level in Chicken Choroid
by: Evgeny Privalov, et al.
Published: (2023-03-01)

Chronic Diarrhea Caused by Vasoactive Intestinal Peptide-Secreting Tumor
by: Oana Belei, et al.
Published: (2023-09-01)

Role of tear vasoactive intestinal peptide on dry eyes after laser keratorefractive surgery
by: Yang Kang, et al.
Published: (2023-04-01)

Attenuated serum vasoactive intestinal peptide concentrations are correlated with disease severity of non-traumatic osteonecrosis of femoral head
by: Ming Liu, et al.
Published: (2021-05-01)

Aviptadil- class effect of a synthetic vasoactive intestinal peptide as a treatment option in COVID-19 patients with severe respiratory failure
by: Dwaipayan Sarathi Chakraborty, et al.
Published: (2022-01-01)

Vasoactive Intestinal Peptide (VIP) Protects Nile Tilapia (<i>Oreochromis niloticus</i>) against <i>Streptococcus agalatiae</i> Infection
by: Zhiqiang Zhang, et al.
Published: (2022-11-01)

PTEN: Tumor Suppressor and Metabolic Regulator
by: Chien-Yu Chen, et al.
Published: (2018-07-01)

The role of vasoactive intestinal peptide (VIP) in atropine-related inhibition of the progression of myopia
by: Ying Wang, et al.
Published: (2024-01-01)

Th17 cells in primary Sjögren’s syndrome negatively correlate with increased Roseburia and Coprococcus
by: Xiaohong Xin, et al.
Published: (2022-10-01)

Drastic decline in vasoactive intestinal peptide expression in the suprachiasmatic nucleus in obese mice on a long-term high-fat diet
by: Domingo Afonso-Oramas, et al.
Published: (2023-10-01)

Pathogenesis and treatment of Sjogren’s syndrome: Review and update
by: Qipeng Zhan, et al.
Published: (2023-02-01)

Metabolic Associated Fatty Liver Disease as a Risk Factor for the Development of Central Nervous System Disorders
by: Sayuri Yoshikawa, et al.
Published: (2023-01-01)

Double Deletion of PI3K and PTEN Modifies Lens Postnatal Growth and Homeostasis
by: Caterina Sellitto, et al.
Published: (2022-08-01)

Vasoactive Intestinal Polypeptide Plays a Key Role in the Microbial-Neuroimmune Control of Intestinal MotilitySummary
by: Xiaopeng Bai, et al.
Published: (2024-01-01)

Vasoactive Intestinal Polypeptide in the Carotid Body—A History of Forty Years of Research. A Mini Review
by: Slawomir Gonkowski
Published: (2020-06-01)

Human CD4<sup>+</sup>CD45RA<sup>+</sup> T Cells Behavior after In Vitro Activation: Modulatory Role of Vasoactive Intestinal Peptide
by: Raúl Villanueva-Romero, et al.
Published: (2022-02-01)

Inhibition of the AKT/mTOR pathway negatively regulates PTEN expression via miRNAs
by: Wan Linyan, et al.
Published: (2022-10-01)

Human umbilical cord mesenchymal stem cells improve disease characterization of Sjogren's syndrome in NOD mice through regulation of gut microbiota and Treg/Th17 cellular immunity
by: Yao Zou, et al.
Published: (2024-01-01)

lncNALT knockdown ameliorates hypertensive retinopathy via PTEN/PI3K/AKT pathway
by: Haijun Kang, et al.
Published: (2022-12-01)

Regulatory role of PI16 in autoimmune arthritis and intestinal inflammation: implications for Treg cell differentiation and function
by: Yuankai Sun, et al.
Published: (2024-04-01)

Iron regulates chondrocyte phenotype in haemophilic cartilage through the PTEN/PI3 K/AKT/FOXO1 pathway
by: Liujie Zheng, et al.
Published: (2023-12-01)

Atorvastatin Inhibits Myocardial Apoptosis in a Swine Model of Coronary Microembolization by Regulating PTEN/PI3K/Akt Signaling Pathway
by: Jiangyou Wang, et al.
Published: (2016-01-01)

The immunomodulation role of Th17 and Treg in renal transplantation
by: Dan-Lei Huang, et al.
Published: (2023-02-01)

T CELL EFFECTOR AND REGULATORY SUBSETS, DIFFERENTIATING BETWEEN ACTIVE AND LATENT MTB INFECTION
by: Yana Todorova, et al.
Published: (2019-12-01)

Formononetin reverses Treg/Th17 imbalance in immune-mediated bone marrow failure mice by regulating the PI3K/Akt signaling pathway
by: Huixuan Lan, et al.
Published: (2024-03-01)

Altered subgroups of regulatory T cells in patients with primary Sjögren's syndrome
by: Jing-Chi Lin, et al.
Published: (2023-05-01)

TRIM37 interacts with PTEN to promote the growth of human T-cell acute lymphocytic leukemia cells through regulating PI3K/AKT pathway
by: Honglan Qu, et al.
Published: (2023-02-01)

Overexpressing miR-122-5p Inhibits the Relaxation of Vaginal Smooth Muscle in Female Sexual Arousal Disorder by Targeting Vasoactive Intestinal Peptide Receptor 1
by: Shengnan Cong, MS, et al.
Published: (2021-08-01)

Circ VRK1/microRNA-17/PTEN axis modulates the angiogenesis of human brain microvascular endothelial cells to affect injury induced by oxygen-glucose deprivation/reperfusion
by: Lei Yang, et al.
Published: (2023-01-01)

Lactobacillus casei ATCC 393 combined with vasoactive intestinal peptide alleviates dextran sodium sulfate-induced ulcerative colitis in C57BL/6 mice via NF-κB and Nrf2 signaling pathways
by: Lixu Zhu, et al.
Published: (2023-09-01)

The PTEN Conundrum: How to Target PTEN-Deficient Prostate Cancer
by: Daniel J. Turnham, et al.
Published: (2020-10-01)

Multifaceted Regulation of PTEN Subcellular Distributions and Biological Functions
by: Tian Liu, et al.
Published: (2019-08-01)

PTEN, a Barrier for Proliferation and Metastasis of Gastric Cancer Cells: From Molecular Pathways to Targeting and Regulation
by: Milad Ashrafizadeh, et al.
Published: (2020-08-01)

YB-1 Oncoprotein Controls PI3K/Akt Pathway by Reducing Pten Protein Level
by: Antonella Delicato, et al.
Published: (2021-09-01)

Role of Matricellular CCN Proteins in Skeletal Muscle: Focus on CCN2/CTGF and Its Regulation by Vasoactive Peptides
by: Daniela L. Rebolledo, et al.
Published: (2021-05-01)

Zebrafish <i>pten</i> Genes Play Relevant but Distinct Roles in Antiviral Immunity
by: Patricia Pereiro, et al.
Published: (2020-04-01)

Decreased TLR4 expression on monocytes may cause regulatory T cells abnormality in patients with primary immune thrombocytopenia
by: Yating Hao, et al.
Published: (2017-07-01)