Endophilin-A1 BAR domain interaction with arachidonyl CoA

Endophilin-A1 BAR domain interaction with arachidonyl CoA

Endophilin-A1 belongs to the family of BAR domain containing proteins that catalyze membrane remodeling processes via sensing, inducing and stabilizing membrane curvature. We show that the BAR domain of endophilin-A1 binds arachidonic acid and molds its coenzyme A (CoA) activated form, arachidonyl-C...

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Bibliographic Details
Main Authors: Maxim V. Petoukhov, Winfried eWeissenhorn, Dmitri I Svergun
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-10-01
Series:Frontiers in Molecular Biosciences
Subjects:
Endocytosis
Molecular modeling
membrane curvature
saturated fatty acid
Endophilin
BAR domain
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmolb.2014.00020/full

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