NBDHEX re‐sensitizes adriamycin‐resistant breast cancer by inhibiting glutathione S‐transferase pi

NBDHEX re‐sensitizes adriamycin‐resistant breast cancer by inhibiting glutathione S‐transferase pi

Abstract Purpose Adriamycin is a novel chemotherapeutic agent of great benefit for treating breast cancer. However, adriamycin ‐resistance remains a major obstacle. The vital Glutathione transferase P1 (GSTPi) inhibitor 6‐(7‐nitro‐2,1,3‐benzoxadiazol‐4‐ylthio) hexanol (NBDHEX) has recently shown ant...

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Bibliographic Details
Main Authors: Huanhuan Sha, Renrui Zou, Ya Lu, Yujie Gan, Rong Ma, Jifeng Feng, Dan Chen
Format: Article
Language:English
Published: Wiley 2023-03-01
Series:Cancer Medicine
Subjects:
adriamycin
breast cancer
GSTpi
NBDHEX
resistant
Online Access:https://doi.org/10.1002/cam4.5370

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