"Omics" studies on carbon nanoparticles effects
Nanoparticles are being explored for biomedical applications in diagnostics and therapeutics. However, biocompatibility, toxicity and cellular entry ability are critical factors that will determine the utility of nanoparticles in clinical applications. "Omics" technologies can provide pow...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Universidade Federal de Uberlândia
2015-06-01
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| Series: | Bioscience Journal |
| Online Access: | https://seer-dev.ufu.br/index.php/biosciencejournal/article/view/28473 |
| _version_ | 1818288028722921472 |
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| author | Liudy Garcia Hernandez Foued Salmen Espindola Luis Felipe Desdin García |
| author_facet | Liudy Garcia Hernandez Foued Salmen Espindola Luis Felipe Desdin García |
| author_sort | Liudy Garcia Hernandez |
| collection | DOAJ |
| description |
Nanoparticles are being explored for biomedical applications in diagnostics and therapeutics. However, biocompatibility, toxicity and cellular entry ability are critical factors that will determine the utility of nanoparticles in clinical applications. "Omics" technologies can provide powerful tools that are sensitive and complementary for the study of molecular toxicology and for biomedical applications of nanomaterials. Specifically, proteomics could elucidate mechanisms of action and contribute to studies on how nanomaterials affect protein expression in tissues and organs, metabolic pathways, signal transduction mechanisms and target molecules. The objective of this review is to present a small approach about "omics" technologies applied to the study of the effect of carbon nanomaterials in the cell.
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| first_indexed | 2024-12-13T01:49:52Z |
| format | Article |
| id | doaj.art-63b6c94a35e3483eb0a61d67ad6b3b6b |
| institution | Directory Open Access Journal |
| issn | 1981-3163 |
| language | English |
| last_indexed | 2024-12-13T01:49:52Z |
| publishDate | 2015-06-01 |
| publisher | Universidade Federal de Uberlândia |
| record_format | Article |
| series | Bioscience Journal |
| spelling | doaj.art-63b6c94a35e3483eb0a61d67ad6b3b6b2022-12-22T00:03:33ZengUniversidade Federal de UberlândiaBioscience Journal1981-31632015-06-01314"Omics" studies on carbon nanoparticles effects Liudy Garcia HernandezFoued Salmen EspindolaLuis Felipe Desdin García Nanoparticles are being explored for biomedical applications in diagnostics and therapeutics. However, biocompatibility, toxicity and cellular entry ability are critical factors that will determine the utility of nanoparticles in clinical applications. "Omics" technologies can provide powerful tools that are sensitive and complementary for the study of molecular toxicology and for biomedical applications of nanomaterials. Specifically, proteomics could elucidate mechanisms of action and contribute to studies on how nanomaterials affect protein expression in tissues and organs, metabolic pathways, signal transduction mechanisms and target molecules. The objective of this review is to present a small approach about "omics" technologies applied to the study of the effect of carbon nanomaterials in the cell. https://seer-dev.ufu.br/index.php/biosciencejournal/article/view/28473 |
| spellingShingle | Liudy Garcia Hernandez Foued Salmen Espindola Luis Felipe Desdin García "Omics" studies on carbon nanoparticles effects Bioscience Journal |
| title | "Omics" studies on carbon nanoparticles effects |
| title_full | "Omics" studies on carbon nanoparticles effects |
| title_fullStr | "Omics" studies on carbon nanoparticles effects |
| title_full_unstemmed | "Omics" studies on carbon nanoparticles effects |
| title_short | "Omics" studies on carbon nanoparticles effects |
| title_sort | omics studies on carbon nanoparticles effects |
| url | https://seer-dev.ufu.br/index.php/biosciencejournal/article/view/28473 |
| work_keys_str_mv | AT liudygarciahernandez omicsstudiesoncarbonnanoparticleseffects AT fouedsalmenespindola omicsstudiesoncarbonnanoparticleseffects AT luisfelipedesdingarcia omicsstudiesoncarbonnanoparticleseffects |