Increased expression of ATP‐binding cassette transporters in enfortumab vedotin‐resistant urothelial cancer

Increased expression of ATP‐binding cassette transporters in enfortumab vedotin‐resistant urothelial cancer

Introduction In addition to reduced nectin‐4 expression, the upregulation of ATP‐binding cassette transporters has been suggested as a potential mechanism of resistance to enfortumab vedotin. Case presentation A 76‐year‐old man previously treated with platinum‐containing chemotherapy and pembrolizum...

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Bibliographic Details
Main Authors: Mariko Kotono, Toshiki Kijima, Atsuko Takada‐Owada, Naoya Okubo, Ryo Kurashina, Hidetoshi Kokubun, Toshitaka Uematsu, Kohei Takei, Kazuyuki Ishida, Takao Kamai
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:IJU Case Reports
Subjects:
ABC transporters
antibody‐drug conjugate
enfortumab vedotin
nectin‐4
urothelial cancer
Online Access:https://doi.org/10.1002/iju5.12696

Internet

https://doi.org/10.1002/iju5.12696

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