The prognostic role of PD-L1 expression and the presence of polyomavirus in Merkel cell carcinoma cases

The prognostic role of PD-L1 expression and the presence of polyomavirus in Merkel cell carcinoma cases

Abstract Background Merkel cell carcinoma (MCC) comprises a rare malignant primary skin tumor presenting neuroendocrine differentiation. Recently, agents blocking the programmed cell death protein 1 and programmed cell death protein ligand 1 pathway (PD-1/PD-L1) have demonstrated objective and durab...

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Bibliographic Details
Main Authors: Stella Meireles Siqueira, Gabriella Campos-do-Carmo, Paulo Ricardo Garcia da Silva, Isabele Ávila Small, Andreia Cristina De Melo
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Infectious Agents and Cancer
Subjects:
Merkel cell carcinoma
Merkel cell polyomavirus
Programmed death ligand-1
Skin cancer
Online Access:https://doi.org/10.1186/s13027-023-00564-1

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