The Roles of Inflammasomes in Host Defense against <i>Mycobacterium tuberculosis</i>

The Roles of Inflammasomes in Host Defense against <i>Mycobacterium tuberculosis</i>

<i>Mycobacterium tuberculosis</i> (MTB) infection is characterized by granulomatous lung lesions and systemic inflammatory responses during active disease. Inflammasome activation is involved in regulation of inflammation. Inflammasomes are multiprotein complexes serving a platform for a...

Full description

Bibliographic Details
Main Authors:	Jialu Ma, Shasha Zhao, Xiao Gao, Rui Wang, Juan Liu, Xiangmei Zhou, Yang Zhou
Format:	Article
Language:	English
Published:	MDPI AG 2021-01-01
Series:	Pathogens
Subjects:	<i>Mycobacterium tuberculosis</i> inflammasome NLRP3 AIM2 IFN
Online Access:	https://www.mdpi.com/2076-0817/10/2/120

Similar Items

Mycobacterium tuberculosis and the host cell inflammasome: a complex relationship.
by: Volker eBriken, et al.
Published: (2013-10-01)

Baicalein Suppresses NLRP3 and AIM2 Inflammasome-Mediated Pyroptosis in Macrophages Infected by Mycobacterium tuberculosis via Induced Autophagy
by: Bangzuo Ning, et al.
Published: (2023-06-01)

Exploring the Use of Medicinal Plants and Their Bioactive Derivatives as Alveolar NLRP3 Inflammasome Regulators during <i>Mycobacterium tuberculosis</i> Infection
by: Nontobeko E. Mvubu, et al.
Published: (2021-08-01)

The Role of NLRP1, NLRP3, and AIM2 Inflammasomes in Psoriasis: Review
by: Magdalena Ciążyńska, et al.
Published: (2021-05-01)

BCG-Vaccinated Children with Contact to Tuberculosis Patients Show Delayed Conversion of <i>Mycobacterium tuberculosis</i>-Specific IFN-γ Release
by: Dorcas O. Owusu, et al.
Published: (2023-04-01)

Inflammasomes in rheumatoid arthritis: a pilot study
by: Qi Jiang, et al.
Published: (2023-10-01)

<i>S100A4</i> Promotes BCG-Induced Pyroptosis of Macrophages by Activating the NF-κB/NLRP3 Inflammasome Signaling Pathway
by: Mengyuan Li, et al.
Published: (2023-08-01)

Insight Into Inflammasome Signaling: Implications for Toxoplasma gondii Infection
by: Yang Wang, et al.
Published: (2020-12-01)

Inflammasome: structure, biological functions, and therapeutic targets
by: Yali Dai, et al.
Published: (2023-10-01)

Promiscuous Inflammasomes: The False Dichotomy of RNA/DNA Virus-Induced Inflammasome Activation and Pyroptosis
by: Hannah L. Wallace, et al.
Published: (2022-09-01)

Combining Host Genetics and Functional Analysis to Depict Inflammasome Contribution in Tuberculosis Susceptibility and Outcome in Endemic Areas
by: Dhêmerson Souza De Lima, et al.
Published: (2020-10-01)

Detecting DNA: An Overview of DNA Recognition by Inflammasomes and Protection against Bacterial Respiratory Infections
by: Juselyn D. Tupik, et al.
Published: (2022-05-01)

The Interplay between <i>Mycobacterium tuberculosis</i> and Human Microbiome
by: Michelle Nguyen, et al.
Published: (2024-01-01)

Activation and Pharmacological Regulation of Inflammasomes
by: Chen Chen, et al.
Published: (2022-07-01)

Neutrophils in <i>Mycobacterium tuberculosis</i>
by: Cheldon Ann Alcantara, et al.
Published: (2023-03-01)

Genetics and Pathogenetic Role of Inflammasomes in Philadelphia Negative Chronic Myeloproliferative Neoplasms: A Narrative Review
by: Valeria Di Battista, et al.
Published: (2021-01-01)

High cell-free DNA is associated with disease progression, inflammasome activation and elevated levels of inflammasome-related cytokine IL-18 in patients with myelofibrosis
by: Geraldine De Luca, et al.
Published: (2023-11-01)

<i>Mycobacterium tuberculosis</i> Resides in Macrophages in Laryngeal Tuberculosis: A Case Report
by: Wafaa Achache, et al.
Published: (2023-11-01)

Potential IFNγ Modulation of Inflammasome Pathway in <i>Chlamydia trachomatis</i> Infected Synovial Cells
by: Simone Filardo, et al.
Published: (2021-12-01)

Inflammasomes cross-talk with lymphocytes to connect the innate and adaptive immune response
by: Hongliang Zhang, et al.
Published: (2023-12-01)

The NLRP3 Inflammasome as a Novel Therapeutic Target for Cardiac Fibrosis
by: Fan J, et al.
Published: (2022-07-01)

<i>Toxoplasma gondii</i> Rhoptry Protein 7 (ROP7) Interacts with NLRP3 and Promotes Inflammasome Hyperactivation in THP-1-Derived Macrophages
by: Lijun Zhu, et al.
Published: (2022-05-01)

Effects of Everolimus in Modulating the Host Immune Responses against <i>Mycobacterium tuberculosis</i> Infection
by: Anmol Raien, et al.
Published: (2023-11-01)

Neutrophils in Tuberculosis: Cell Biology, Cellular Networking and Multitasking in Host Defense
by: Rachana R. Borkute, et al.
Published: (2021-04-01)

Role of type I interferons in inflammasome activation, cell death and disease during microbial infection
by: R. K. Subbarao eMalireddi, et al.
Published: (2013-11-01)

Comparative Proteomic Analysis of Exosomes Derived from Patients Infected with Non-Tuberculous Mycobacterium and <i>Mycobacterium tuberculosis</i>
by: Li Wang, et al.
Published: (2023-09-01)

AIM2 inflammasome activation may mediate high mobility group box 1 release in murine allergic rhinitis
by: Yan Wang, et al.
Published: (2022-11-01)

Metabolic Versatility of <i>Mycobacterium tuberculosis</i> during Infection and Dormancy
by: Dorothy Pei Shan Chang, et al.
Published: (2021-02-01)

<i>Mycobacterium microti</i> Interferes with Bovine Tuberculosis Surveillance
by: Lorraine Michelet, et al.
Published: (2020-11-01)

Tools to Alleviate the Drug Resistance in <i>Mycobacterium tuberculosis</i>
by: Ali A. Rabaan, et al.
Published: (2022-10-01)

Correlation between Inflammasomes and Microbiota in Peri-Implantitis
by: Miguel Padial-Molina, et al.
Published: (2024-01-01)

Whole Genome Sequence Analysis of <i>Mycobacterium bovis</i> Cattle Isolates, Algeria
by: Fatah Tazerart, et al.
Published: (2021-06-01)

A Paradox in Bacterial Pathogenesis: Activation of the Local Macrophage Inflammasome Is Required for Virulence of <i>Streptococcus uberis</i>
by: Nathan Archer, et al.
Published: (2020-11-01)

Quinoxaline Moiety: A Potential Scaffold against <i>Mycobacterium tuberculosis</i>
by: Marc Montana, et al.
Published: (2021-08-01)

Microscopic Observation Drug Susceptibility (MODS) Assay: A Convenient Method for Determining Antibiogram of Clinical Isolates of <i>Mycobacterium tuberculosis</i> in Ghana
by: Enid Owusu, et al.
Published: (2020-01-01)

<i>Mycobacterium tuberculosis</i> Affects Protein and Lipid Content of Circulating Exosomes in Infected Patients Depending on Tuberculosis Disease State
by: Fantahun Biadglegne, et al.
Published: (2022-03-01)

Expression of NLRP3 inflammasome in leprosy indicates immune evasion of Mycobacterium leprae
by: Ana Luisa Gomes Mendes, et al.
Published: (2020-02-01)

Identification of New <i>Mycobacterium tuberculosis</i> Proteasome Inhibitors Using a Knowledge-Based Computational Screening Approach
by: Tahani M. Almeleebia, et al.
Published: (2021-04-01)

Molecular Mechanisms of Inflammasome in Ischemic Stroke Pathogenesis
by: Maria Grazia Puleo, et al.
Published: (2022-09-01)

A type I IFN-dependent DNA damage response regulates the genetic program and inflammasome activation in macrophages
by: Abigail J Morales, et al.
Published: (2017-03-01)