A Simulation Model of Periarterial Clearance of Amyloid-beta from the Brain

A Simulation Model of Periarterial Clearance of Amyloid-beta from the Brain

The accumulation of soluble and insoluble amyloid-beta (A-beta) in the brain indicates failure of elimination of A-beta from the brain with age and Alzheimer's disease. There is a variety of mechanisms for elimination of A-beta from the brain. They include the action of microglia and enzymes to...

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Bibliographic Details
Main Authors:	Alexandra Katharina Diem, Mingyi eTan, Neil W. Bressloff, Cheryl eHawkes, Alan W. J. Morris, Roy O. Weller, Roxana O. Carare
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2016-02-01
Series:	Frontiers in Aging Neuroscience
Subjects:	Brain Cerebral Amyloid Angiopathy Diffusion Alzheimer's disease Dextran simulation model
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fnagi.2016.00018/full

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