Oromandibular dystonia secondary to methylphenidate: A case report and literature review
Methylphenidate (MTP) is a first-line treatment for attention-deficit hyperactivity disorder (ADHD) in children and adults and as a second-line treatment for narcolepsy in adults. We report a case of a young adult male who presented with abnormal orofacial movements after MTP use for the management...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Kashan University of Medical Sciences
2020-01-01
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| Series: | International Archives of Health Sciences |
| Subjects: | |
| Online Access: | http://www.iahs.kaums.ac.ir/article.asp?issn=2383-2568;year=2020;volume=7;issue=2;spage=108;epage=111;aulast=Rissardo |
| _version_ | 1827610542820294656 |
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| author | Jamir Pitton Rissardo Ana Letícia Fornari Caprara |
| author_facet | Jamir Pitton Rissardo Ana Letícia Fornari Caprara |
| author_sort | Jamir Pitton Rissardo |
| collection | DOAJ |
| description | Methylphenidate (MTP) is a first-line treatment for attention-deficit hyperactivity disorder (ADHD) in children and adults and as a second-line treatment for narcolepsy in adults. We report a case of a young adult male who presented with abnormal orofacial movements after MTP use for the management of ADHD. Laboratory tests were within normal limits. His family history was unremarkable and negative for neurological diseases. A dose of MTP was given during the neurological examination, and abnormal facial movements suggestive of oromandibular dystonia (DTN) were observed. MTP was withdrawn and the symptoms recovered. The oromandibular DTN secondary to MTP probably occurs due to influences in the dopaminergic pathway, and these dyskinetic movements may be associated with a disbalance state of the dopamine, in which an increase or decrease of this neurotransmitter could lead to abnormal movements. |
| first_indexed | 2024-03-09T07:52:37Z |
| format | Article |
| id | doaj.art-63c93edb16b44e369bc1329aaa4bd61d |
| institution | Directory Open Access Journal |
| issn | 2383-2568 |
| language | English |
| last_indexed | 2024-03-09T07:52:37Z |
| publishDate | 2020-01-01 |
| publisher | Kashan University of Medical Sciences |
| record_format | Article |
| series | International Archives of Health Sciences |
| spelling | doaj.art-63c93edb16b44e369bc1329aaa4bd61d2023-12-03T01:29:11ZengKashan University of Medical SciencesInternational Archives of Health Sciences2383-25682020-01-017210811110.4103/iahs.iahs_71_19Oromandibular dystonia secondary to methylphenidate: A case report and literature reviewJamir Pitton RissardoAna Letícia Fornari CapraraMethylphenidate (MTP) is a first-line treatment for attention-deficit hyperactivity disorder (ADHD) in children and adults and as a second-line treatment for narcolepsy in adults. We report a case of a young adult male who presented with abnormal orofacial movements after MTP use for the management of ADHD. Laboratory tests were within normal limits. His family history was unremarkable and negative for neurological diseases. A dose of MTP was given during the neurological examination, and abnormal facial movements suggestive of oromandibular dystonia (DTN) were observed. MTP was withdrawn and the symptoms recovered. The oromandibular DTN secondary to MTP probably occurs due to influences in the dopaminergic pathway, and these dyskinetic movements may be associated with a disbalance state of the dopamine, in which an increase or decrease of this neurotransmitter could lead to abnormal movements.http://www.iahs.kaums.ac.ir/article.asp?issn=2383-2568;year=2020;volume=7;issue=2;spage=108;epage=111;aulast=Rissardodystoniamethylphenidateoromandibular dystoniatongue movements |
| spellingShingle | Jamir Pitton Rissardo Ana Letícia Fornari Caprara Oromandibular dystonia secondary to methylphenidate: A case report and literature review International Archives of Health Sciences dystonia methylphenidate oromandibular dystonia tongue movements |
| title | Oromandibular dystonia secondary to methylphenidate: A case report and literature review |
| title_full | Oromandibular dystonia secondary to methylphenidate: A case report and literature review |
| title_fullStr | Oromandibular dystonia secondary to methylphenidate: A case report and literature review |
| title_full_unstemmed | Oromandibular dystonia secondary to methylphenidate: A case report and literature review |
| title_short | Oromandibular dystonia secondary to methylphenidate: A case report and literature review |
| title_sort | oromandibular dystonia secondary to methylphenidate a case report and literature review |
| topic | dystonia methylphenidate oromandibular dystonia tongue movements |
| url | http://www.iahs.kaums.ac.ir/article.asp?issn=2383-2568;year=2020;volume=7;issue=2;spage=108;epage=111;aulast=Rissardo |
| work_keys_str_mv | AT jamirpittonrissardo oromandibulardystoniasecondarytomethylphenidateacasereportandliteraturereview AT analeticiafornaricaprara oromandibulardystoniasecondarytomethylphenidateacasereportandliteraturereview |