Signalling-dependent adverse health effects of carbon nanoparticles are prevented by the compatible solute mannosylglycerate (firoin) in vitro and in vivo.

The inhalation of combustion-derived nanoparticles leads to adverse health effects in the airways. In this context the induction of membrane-coupled signalling is considered as causative for changes in tissue homeostasis and pro-inflammatory reactions. The identification of these molecular cell reac...

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Main Authors: Andrea Autengruber, Ulrich Sydlik, Matthias Kroker, Tamara Hornstein, Niloofar Ale-Agha, Daniel Stöckmann, Andreas Bilstein, Catrin Albrecht, Adnana Paunel-Görgülü, Christoph V Suschek, Jean Krutmann, Klaus Unfried
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4240547?pdf=render