Tuberculosis of the Thyroid
Objectives: To present a case of thyroid tuberculosis and to discuss its clinical presentation, differential diagnoses and management. Methods: Design: Case Report Setting: Tertiary Government Hospital Patient: One...
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| Format: | Article |
| Language: | English |
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Philippine Society of Otolaryngology-Head and Neck Surgery, Inc.
2017-06-01
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| Series: | Philippine Journal of Otolaryngology Head and Neck Surgery |
| Subjects: | |
| Online Access: | https://pjohns.pso-hns.org/index.php/pjohns/article/view/189 |
| _version_ | 1830213826663940096 |
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| author | Elmer F. Fabito Mary Jane Tipayno-Lubos Felixberto D. Ayahao |
| author_facet | Elmer F. Fabito Mary Jane Tipayno-Lubos Felixberto D. Ayahao |
| author_sort | Elmer F. Fabito |
| collection | DOAJ |
| description | Objectives: To present a case of thyroid tuberculosis and to discuss its clinical presentation, differential diagnoses and management.
Methods:
Design: Case Report
Setting: Tertiary Government Hospital
Patient: One
Results: A 55-year-old farmer presented with an 8-month progressively enlarging anterior neck mass, and fine needle aspiration biopsy yielded grossly turbid straw-colored aspirate admixed with blood with microscopy showing scattered inflammatory cells and macrophages set against a colloid background. After total thyroidectomy, hispathology revealed parenchymal infiltration by multiple aggregates of plump spindled to epitheloid cells forming granulomas with interspersed multinucleated giant cells, central caseation necrosis and surrounding fibrosis with chronic inflammatory infiltrates. The nodal masses also showed prominent germinal centers with interspersed epitheloid cells and foamy macrophages. Final diagnosis was chronic granulomatous inflammation consistent with tuberculosis.
Conclusion: Tuberculosis (TB) of the thyroid is a rare occurrence that can present as inflammation, infection or tumor formation of the thyroid gland. Diagnosis depends on identification of the tubercle from tissues and aspirates by acid fast staining and TB culture. Treatment consists of multiple drug therapy for tuberculosis but thyroidectomy may be an option if the thyroid gland is severely diseased.
Keywords: tuberculosis, endocrine; thyroid disease |
| first_indexed | 2024-12-18T06:30:41Z |
| format | Article |
| id | doaj.art-63ca477709804dccb3dc3db96dc48e94 |
| institution | Directory Open Access Journal |
| issn | 1908-4889 2094-1501 |
| language | English |
| last_indexed | 2024-12-18T06:30:41Z |
| publishDate | 2017-06-01 |
| publisher | Philippine Society of Otolaryngology-Head and Neck Surgery, Inc. |
| record_format | Article |
| series | Philippine Journal of Otolaryngology Head and Neck Surgery |
| spelling | doaj.art-63ca477709804dccb3dc3db96dc48e942022-12-21T21:17:54ZengPhilippine Society of Otolaryngology-Head and Neck Surgery, Inc.Philippine Journal of Otolaryngology Head and Neck Surgery1908-48892094-15012017-06-0132110.32412/pjohns.v32i1.189Tuberculosis of the ThyroidElmer F. Fabito0Mary Jane Tipayno-Lubos1Felixberto D. Ayahao2Department of Ear Nose Throat – Head and Neck Surgery Baguio General Hospital and Medical CenterDepartment of Ear Nose Throat – Head and Neck Surgery Baguio General Hospital and Medical CenterDepartment of Ear Nose Throat – Head and Neck Surgery Baguio General Hospital and Medical CenterObjectives: To present a case of thyroid tuberculosis and to discuss its clinical presentation, differential diagnoses and management. Methods: Design: Case Report Setting: Tertiary Government Hospital Patient: One Results: A 55-year-old farmer presented with an 8-month progressively enlarging anterior neck mass, and fine needle aspiration biopsy yielded grossly turbid straw-colored aspirate admixed with blood with microscopy showing scattered inflammatory cells and macrophages set against a colloid background. After total thyroidectomy, hispathology revealed parenchymal infiltration by multiple aggregates of plump spindled to epitheloid cells forming granulomas with interspersed multinucleated giant cells, central caseation necrosis and surrounding fibrosis with chronic inflammatory infiltrates. The nodal masses also showed prominent germinal centers with interspersed epitheloid cells and foamy macrophages. Final diagnosis was chronic granulomatous inflammation consistent with tuberculosis. Conclusion: Tuberculosis (TB) of the thyroid is a rare occurrence that can present as inflammation, infection or tumor formation of the thyroid gland. Diagnosis depends on identification of the tubercle from tissues and aspirates by acid fast staining and TB culture. Treatment consists of multiple drug therapy for tuberculosis but thyroidectomy may be an option if the thyroid gland is severely diseased. Keywords: tuberculosis, endocrine; thyroid diseasehttps://pjohns.pso-hns.org/index.php/pjohns/article/view/189tuberculosis, endocrine; thyroid disease |
| spellingShingle | Elmer F. Fabito Mary Jane Tipayno-Lubos Felixberto D. Ayahao Tuberculosis of the Thyroid Philippine Journal of Otolaryngology Head and Neck Surgery tuberculosis, endocrine; thyroid disease |
| title | Tuberculosis of the Thyroid |
| title_full | Tuberculosis of the Thyroid |
| title_fullStr | Tuberculosis of the Thyroid |
| title_full_unstemmed | Tuberculosis of the Thyroid |
| title_short | Tuberculosis of the Thyroid |
| title_sort | tuberculosis of the thyroid |
| topic | tuberculosis, endocrine; thyroid disease |
| url | https://pjohns.pso-hns.org/index.php/pjohns/article/view/189 |
| work_keys_str_mv | AT elmerffabito tuberculosisofthethyroid AT maryjanetipaynolubos tuberculosisofthethyroid AT felixbertodayahao tuberculosisofthethyroid |