Optimizing antibiotics in residents of nursing homes: protocol of a randomized trial

<p>Abstract</p> <p>Background</p> <p>Antibiotics are frequently prescribed for older adults who reside in long-term care facilities. A substantial proportion of antibiotic use in this setting is inappropriate. Antibiotics are often prescribed for asymptomatic bacteriuri...

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Main Authors: Simor Andrew, McGeer Allison, Lohfeld Lynne, Brazil Kevin, Loeb Mark, Stevenson Kurt, Walter Stephen, Zoutman Dick
Format: Article
Language:English
Published: BMC 2002-09-01
Series:BMC Health Services Research
Online Access:http://www.biomedcentral.com/1472-6963/2/17
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author Simor Andrew
McGeer Allison
Lohfeld Lynne
Brazil Kevin
Loeb Mark
Stevenson Kurt
Walter Stephen
Zoutman Dick
author_facet Simor Andrew
McGeer Allison
Lohfeld Lynne
Brazil Kevin
Loeb Mark
Stevenson Kurt
Walter Stephen
Zoutman Dick
author_sort Simor Andrew
collection DOAJ
description <p>Abstract</p> <p>Background</p> <p>Antibiotics are frequently prescribed for older adults who reside in long-term care facilities. A substantial proportion of antibiotic use in this setting is inappropriate. Antibiotics are often prescribed for asymptomatic bacteriuria, a condition for which randomized trials of antibiotic therapy indicate no benefit and in fact harm. This proposal describes a randomized trial of diagnostic and therapeutic algorithms to reduce the use of antibiotics in residents of long-term care facilities.</p> <p>Methods</p> <p>In this on-going study, 22 nursing homes have been randomized to either use of algorithms (11 nursing homes) or to usual practise (11 nursing homes). The algorithms describe signs and symptoms for which it would be appropriate to send urine cultures or to prescribe antibiotics. The algorithms are introduced by inservicing nursing staff and by conducting one-on-one sessions for physicians using case-scenarios. The primary outcome of the study is courses of antibiotics per 1000 resident days. Secondary outcomes include urine cultures sent and antibiotic courses for urinary indications. Focus groups and semi-structured interviews with key informants will be used to assess the process of implementation and to identify key factors for sustainability.</p>
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spelling doaj.art-63cb614b438a4e29a1b7bc9ee736561f2022-12-21T23:16:30ZengBMCBMC Health Services Research1472-69632002-09-01211710.1186/1472-6963-2-17Optimizing antibiotics in residents of nursing homes: protocol of a randomized trialSimor AndrewMcGeer AllisonLohfeld LynneBrazil KevinLoeb MarkStevenson KurtWalter StephenZoutman Dick<p>Abstract</p> <p>Background</p> <p>Antibiotics are frequently prescribed for older adults who reside in long-term care facilities. A substantial proportion of antibiotic use in this setting is inappropriate. Antibiotics are often prescribed for asymptomatic bacteriuria, a condition for which randomized trials of antibiotic therapy indicate no benefit and in fact harm. This proposal describes a randomized trial of diagnostic and therapeutic algorithms to reduce the use of antibiotics in residents of long-term care facilities.</p> <p>Methods</p> <p>In this on-going study, 22 nursing homes have been randomized to either use of algorithms (11 nursing homes) or to usual practise (11 nursing homes). The algorithms describe signs and symptoms for which it would be appropriate to send urine cultures or to prescribe antibiotics. The algorithms are introduced by inservicing nursing staff and by conducting one-on-one sessions for physicians using case-scenarios. The primary outcome of the study is courses of antibiotics per 1000 resident days. Secondary outcomes include urine cultures sent and antibiotic courses for urinary indications. Focus groups and semi-structured interviews with key informants will be used to assess the process of implementation and to identify key factors for sustainability.</p>http://www.biomedcentral.com/1472-6963/2/17
spellingShingle Simor Andrew
McGeer Allison
Lohfeld Lynne
Brazil Kevin
Loeb Mark
Stevenson Kurt
Walter Stephen
Zoutman Dick
Optimizing antibiotics in residents of nursing homes: protocol of a randomized trial
BMC Health Services Research
title Optimizing antibiotics in residents of nursing homes: protocol of a randomized trial
title_full Optimizing antibiotics in residents of nursing homes: protocol of a randomized trial
title_fullStr Optimizing antibiotics in residents of nursing homes: protocol of a randomized trial
title_full_unstemmed Optimizing antibiotics in residents of nursing homes: protocol of a randomized trial
title_short Optimizing antibiotics in residents of nursing homes: protocol of a randomized trial
title_sort optimizing antibiotics in residents of nursing homes protocol of a randomized trial
url http://www.biomedcentral.com/1472-6963/2/17
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